Dental Cavity Clinical Trial
— Caries SpeciesOfficial title:
Prevalence and Identification of Pathogenic Species and Genotypes of Bacterial Diversity in Relation to the Severity of Dental Caries
| Verified date | August 2020 |
| Source | Centre Hospitalier Universitaire de Nimes |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
The primary objective of this study is to estimate the distribution of pathogenic species and genotypes of bacterial diversity in 7 stages ICDAS (International Caries Detection and Assessment System) corresponding to the severity of dental caries among patients aged 3-45 years consulting in the Dentistry Departments of the Nîmes University Hospital and the Montpellier University Hospital.
| Status | Completed |
| Enrollment | 56 |
| Est. completion date | March 8, 2017 |
| Est. primary completion date | March 8, 2017 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 3 Years to 45 Years |
| Eligibility |
Inclusion Criteria: - Volunteers aged 3 to 45 who come in to the hospital for a dental consultation - Minors must have parental permission - The patient must have given his/her informed and signed consent Exclusion Criteria: - The patient is participating in another study - The patient is in an exclusion period determined by a previous study - The patient is pregnant, or breastfeeding - The patient has been on antibiotics within the past two months - Smokers - Teeth under current care - Parodontopathy - Use of a mouthwash within the last week - Insufficient numbers of healthy and/or teeth with carious lesions for carrying out the study |
| Country | Name | City | State |
|---|---|---|---|
| France | CHRU de Montpellier - Centre de Soins, d'Enseignement et de Recherche Dentaires | Montpellier | |
| France | CHRU de Montpellier - Hôpital La Colombière | Montpellier | |
| France | CHRU de Nîmes - Hôpital Universitaire Carémeau | Nîmes Cedex 9 |
| Lead Sponsor | Collaborator |
|---|---|
| Centre Hospitalier Universitaire de Nimes |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Other | Profession (or parents' professions) | baseline (day 0) | ||
| Other | Age | baseline (day 0) | ||
| Other | Sex | baseline (day 0) | ||
| Primary | Bacterial profile | Bacterial profiles will be constructed using saliva and plaque samples. | Baseline (day 0) | |
| Primary | ICDAS assessment | Dental caries will be assessed using the ICDAS (International Caries Detection and Assessment System) system | Baseline (day 0) | |
| Secondary | Studies were stopped during high school? yes/no | baseline (Day 0) | ||
| Secondary | Does the patient have at least five fillings? yes/no | Baseline (day 0) | ||
| Secondary | Does the patient have at least one filling and one missing tooth on the anterior sector following the carious lesion? yes/no | baseline (day 0) | ||
| Secondary | Within the last 12 months, the patient has had dental care or tooth removal following the carious lesion? yes/no | baseline (day 0) | ||
| Secondary | Yesterday, did the patient eat at least three snacks (or sugary or carbonated drinks) between meals? yes/no | Baseline (day 0) | ||
| Secondary | Yesterday, did the patient brush his/her teeth fewer than 2 times? yes/no | baseline (day 0) | ||
| Secondary | The patient has at least one carious lesion restricted to the enamel? yes/no | baseline (day 0) | ||
| Secondary | The patient has at least one carious lesion restricted to the enamel on an anterior tooth or involving the smooth surface on a posterior tooth (yes/no) | baseline (day 0) | ||
| Secondary | The patient has at least one carious lesion attacking the dentin or pulp. yes/no | baseline (day 0) | ||
| Secondary | The patient has at least one carious lesion reaching dentin or pulp on an anterior tooth or on the smooth surface of a posterior tooth (yes/no) | baseline (day 0) |