Iowa Fluoride Study/Iowa Bone Development Study

Status Active, not recruiting

Clinical Trial Summary

A cohort of newborns was recruited for the Iowa Fluoride Study from 1992-95 to assess the complex relationships among fluoride intakes, fluoride exposures, dental fluorosis, and dental caries. Detailed questionnaires were sent every 1.5-6 months concerning water sources, fluoride exposures, dietary intakes, etc. Standardized dental exams were conducted at ~ages 5, 9, 13, 17, and 23. At about age 5, participants were invited to join the offshoot Iowa Bone Development Study. Bone densitometry assessments were conducted at ages 5, 8, 11, 13, 15, 17, 19, and 23. These included Dual-energy X-ray Absorptiometry (DXA) of hip, lumbar spine, and whole body from age 5; peripheral Quantitative Computed Tomography (pQCT) of the radius and tibia from age 11; and Multi-Detector Computed Tomography (MDCT) of the tibia from age 19. Physical activity and other factors also were assessed longitudinally.

Clinical Trial Description

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03547128
Study type	Observational
Source	University of Iowa
Contact
Status	Active, not recruiting
Phase
Start date	March 1, 1992
Completion date	January 15, 2025

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Iowa Fluoride Study/Iowa Bone Development Study — (IFS/IBDS)

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms