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Dental Caries clinical trials

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NCT ID: NCT03187548 Not yet recruiting - White Spot Lesion Clinical Trials

Evaluation of CPP-ACP Prophylactic Effect on Enamel Surface During Orthodontic Treatment

Start date: July 2017
Phase: Phase 1
Study type: Interventional

This study is aiming in preventing the formation of WSL associated with orthodontic treatment which occurs to more than 50% of orthodontically treated patients through applying CPP-ACP on the enamel surface once every 2 weeks for 3 months.

NCT ID: NCT03143023 Not yet recruiting - Dental Caries Clinical Trials

Efficacy of Dentifrices Containing Arginine Versus Fluoride on Microbial Acid

Start date: June 2017
Phase: N/A
Study type: Interventional

This study will be conducted to evaluate the effect of arginine versus fluoride containing toothpaste on neutralization of microbial acid produced by Cariogenic bacteria in adult population using chair side assessment method.

NCT ID: NCT03061916 Not yet recruiting - Dental Caries Clinical Trials

Cinnamon and Ginger in Comparison to Chlorhexidine Gluconate 0.2% on Oral Streptococcus Mutans

Start date: March 2017
Phase: Phase 3
Study type: Interventional

Chlorhexidine is the most potent chemotherapeutic agent against mutans streptococci and dental caries, however, the incidence of side effects such as teeth discoloration, staining of restorations, undesirable taste, discoloration of tongue, dryness and burning sensation in the mouth discourage patients to use this mouth wash. Natural products are now preferred by a large proportion of the population and have been reported to possess antimicrobial activity.These products have recently been shown to be a good alternative to synthetic chemical substances for caries prevention like Cinnamon and Ginger. The aim of this study is to compare the antimicrobial effects of aqueous extracts of cinnamon 20% and ginger 20% in comparison to chlorhexidine gluconate 0.2% on oral streptococcus mutans

NCT ID: NCT03061422 Not yet recruiting - Dental Caries Clinical Trials

Effect of Xylitol-Containing Chewing Gum With/Without Bicarbonate Versus Paraffin Pellet on Salivary pH

Start date: March 3, 2017
Phase: N/A
Study type: Interventional

36 eligible participants will be randomly divided into three groups (n=12) according to the tested chewing gum (A), where (A1) represents participants exposed to xylitol chewing gum, (A2) represents participants exposed to bicarbonate and xylitol chewing gum and (A3) represents control group where participants are exposed to paraffin pellet chewing. The pH of saliva will be evaluated according to time in relation to the gum chewing (T) where (T0) represent the pH before chewing, (T1) represent 5 minutes after gum chewing at fixed time of the day (in the morning from 10 to 11 am). Direct benefit of the research to the human volunteer: It is important for high caries risk patients to decrease caries susceptibility as this will eventually decrease their dental treatments and subsequently the treatment cost. Scientific value and social benefits: This study will benefit the dentist as the main goal of a dentist is to prevent rather than cure. Also, it will decrease the restorative work carried out by dentist and save this time for educating more patients about caries prevention methods. Expected risk to the human subjects: Allergic reactions due to any of the components of the materials used which is rare to occur.

NCT ID: NCT03037814 Not yet recruiting - Dental Caries Clinical Trials

Clinical Performance of Restorative Materials in Primary Teeth

Start date: September 28, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate and compare the clinical performance of dental restorative materials in Class II cavities of primary molar teeth

NCT ID: NCT03002792 Not yet recruiting - Anesthesia Clinical Trials

Neurodevelopment Outcomes After Pediatric Dental Caries Treatment Under General Anaesthesia

Start date: January 2017
Phase: N/A
Study type: Observational

The purpose of this study is to investigate whether early expose to general anaesthesia will influence neurodevelopment.

NCT ID: NCT02969538 Not yet recruiting - Dental Caries Clinical Trials

Effect of Shortening the Etching Time on the Clinical Performance of Resin Composite Restorations in Primary Teeth

Start date: November 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of shortening the etching time on the 18-month clinical performance of resin composite restorations in primary molars after partial carious removal. This randomized clinical trial will include subjects (5-10 year-old children) selected at Pediatric Clinic of Federal University of Santa Maria. The sample will consist of 70 primary molars presenting active cavitated carious lesions (with radiographic involvement of the outer half of the dentin), located on the occlusal surface. The sample will be randomly divided into two groups according to the etching time of the dentin prior adhesive application (Adper Single Bond 2; 3M ESPE): recommend by manufacturers (15 seconds) and half-reduced etching time (7 seconds). The restorations will be clinically followed every 6 months for up to 18-month using the FDI criteria for clinical evaluation. Survival estimates for restoration longevity will be evaluated using the Kaplan-Meier method.

NCT ID: NCT02915419 Not yet recruiting - Carious Teeth Clinical Trials

Evaluation of Survival of Mature Second Premolar Treated With Regenerative Techniques

Start date: October 2016
Phase: N/A
Study type: Interventional

This study aims to compare the ability of different regenerative protocols in the treatment of mature necrotic

NCT ID: NCT02913885 Not yet recruiting - White Spot Lesion Clinical Trials

Effect of Curodont Repair on Color Change of White Spot Lesions

Start date: January 2017
Phase: Phase 2
Study type: Interventional

The aim of this study is to compare the effect of color change between remineralizing agent and guided enamel regeneration in treatment of white spot lesion after orthodontic treatments

NCT ID: NCT02912741 Not yet recruiting - White Spot Lesions Clinical Trials

One Year Clinical Evaluation of White Spot Lesions Treated With Newly Introduced Resin Modified Glass Ionomer in Comparison to Resin Infiltration in Anterior Teeth Split Mouth Technique

Start date: January 2017
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the addition of new technology of resin modified glass-ionomer in comparison to resin infiltration in treating post-orthodontic white spot lesions; both applies into the same patient's mouth; to reveal which material will have more clinical satisfactory performance inside the oral cavity and to overcome the high expensive cost in treating such clinical cases