Discoloration of Carious Primary Teeth After Application of Silver Diamine

Status Not yet recruiting

Clinical Trial Summary

To assess discoloration of carious primary teeth after application of silver diamine fluoride versus sodium fluoride varnish.

Clinical Trial Description

The American Academy of Pediatric Dentistry's (AAPD) guidelines (2017) stated that Silver diamine fluoride (SDF) is a brush-on liquid that arrest 87.7% of dental caries lesions. The success rate is similar for restorations placed under GA. One of the most exciting aspects of SDF is the 67±4% decrease in new lesions on untreated surfaces, achieved simply by treating active lesions .This is not the same as incidence of any new lesions (elaborated above for treatment under GA), however the relation warrants further investigation.

Benefit to the patient

- No pain and infection.

- Enhance child cooperation.

- Enhance better patient compliance.

- Decrease cost of dental treatment and may eliminate the need for General Anesthesia.

Benefit to the dentist

- Develop an effective fast easy method to arrest the caries by using SDF.

- Ease of dental treatment.

- Better cooperation with the child.

- The procedure is simple.

- Inexpensive and non-invasive.

- It does not require expensive equipment or support infrastructure, such as pipe water or electricity.

Benefit to the population

- Reduce the harmful impact of oral health problems in preschool children from low income families.

- SDF can be considered a user-friendly material for use in dental clinics as well as remote areas, schools or deprived communities.

Children aged 2-5 years can benefit from the use of SDF, an easy anticaries treatment. Furthermore, children in this age group may benefit from delayed dental treatment and overall caries arrest, thus reducing potential pain and infection, expensive future emergency room visits, the need for general anesthesia or traumatic dental experiences on uncooperative children. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03557996
Study type	Interventional
Source	Cairo University
Contact	Yousra M Abdel Rehim, MSc
Phone	01273335144
Email	yousra.mohamed@dentistry.cu.edu.eg
Status	Not yet recruiting
Phase	Phase 4
Start date	December 1, 2018
Completion date	June 1, 2020

View Details

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Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Discoloration of Carious Primary Teeth After Application of Silver Diamine Fluoride Versus Sodium Fluoride Varnish

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms