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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT02078336
Other study ID # S55859
Secondary ID 2013-003991-11
Status Recruiting
Phase Phase 4
First received February 24, 2014
Last updated February 28, 2014
Start date December 2013
Est. completion date August 2014

Study information

Verified date November 2013
Source Universitaire Ziekenhuizen Leuven
Contact Dominique Declerck
Email dominique.declerck@med.kuleuven.be
Is FDA regulated No
Health authority Belgium: Ethics CommitteeBelgium: Federal Agency for Medicines and Health Products, FAMHP
Study type Interventional

Clinical Trial Summary

The study aims to compare procedural sedation protocols, specifically applied for the delivery of regular dental care in persons with a mental disability.

The primary objectives are:

- To assess the level of cooperation during regular dental care using different procedural sedation protocols

- To assess patient safety during regular dental care using different sedation protocols

- To assess patient comfort and possible side-effects after regular dental care using different sedation protocols


Recruitment information / eligibility

Status Recruiting
Enrollment 40
Est. completion date August 2014
Est. primary completion date August 2014
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Minimum age 18yrs

- Patient resides at least 6 months in nursing home "het Gielsbos".

- Patient always gets a sedative protocol to make dental care delivery possible.

- Informed consent was obtained from parent/guardian

- No medical contra-indication for any of tested sedative protocols

Exclusion Criteria:

- Age under 18yrs

- The patient is no resident of the nursing home "het Gielsbos" or lives there for less than 6 months.

- No need for medicinal support during dental treatment

- No informed consent was obtained by parents or the guardian of the patient.

- Medical contra-indication for 1 of the sedative protocols

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


Intervention

Drug:
Midazolam Mylan

Lorazepam Mylan

Valium + Akineton + Dehydrobenzperidol + Atropine sulfate


Locations

Country Name City State
Belgium Katholieke Universiteit Leuven Leuven

Sponsors (1)

Lead Sponsor Collaborator
Universitaire Ziekenhuizen Leuven

Country where clinical trial is conducted

Belgium, 

Outcome

Type Measure Description Time frame Safety issue
Primary Level of cooperation of patient when receiving regular dental care Participants will be followed for the duration of the dental treatment, an expected average of 30 minutes. No
Secondary Recording of vital parameters during regular dental care delivery The measure is a composite of
recording of blood pressure
recording of pulse
recording of oxygen saturation
24 hrs No
Secondary Level of patient comfort and possible side-effects after dental treatment session The measure of patient comfort and possible side-effects after dental treatment session is a composite of
changes in appetite
changes in toilet behavior
changes in level of consciousness
changes in level of concentration
changes in pattern of epileptic insults
changes in mood
changes in sleeping pattern
changes in level of motor skills
24 hrs No