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Clinical Trial Summary

The primary objective of this study will explore whether circulating acyl-ghrelin (AG) and unacylated-ghrelin (UAG) are reduced in neurodegenerative disease associated with cognitive impairment. It will focus on validating pilot data generated following the analysis of Parkinson's disease (PD), Parkinson's disease dementia (PDD) and healthy cohorts (IRAS project ID: 250933). In addition to the advantages of study replication we will extend the analysis to include two further patient groups that are associated with cognitive impairments, namely, Alzheimer's dementia (AD) and dementia with Lewy bodies (DLB). This study will increase confidence in the replication of our findings. This will be a cross-sectional study using peripheral venous blood.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05381090
Study type Interventional
Source Swansea University
Contact Paola A Griffiths
Phone 0179260
Email resgov@swansea.ac.uk
Status Recruiting
Phase N/A
Start date August 15, 2022
Completion date September 2024

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