Advanced Cognitive Stimulation Therapy (ACST)

Dementia Clinical Trial

Official title: Feasibility Randomised Controlled Trial (RCT) of Advanced Cognitive Stimulation Therapy (ACST) for People With Moderate to Severe Dementia

Status Not yet recruiting

Clinical Trial Summary

This study is a feasibility randomised controlled trial (RCT) for an evidence-based intervention for people with moderate to severe dementia. The psychosocial intervention is adapted from Cognitive Stimulation Therapy (CST) and developed within the Medical Research Council (MRC) framework.

Clinical Trial Description

The World Health Organization calls for an increase of psychosocial interventions for dementia-a global epidemic. Cognitive Stimulation Therapy (CST) is the only non-pharmacological therapy recommended by the National Institute for Health and Care Excellence for improving cognition for mild to moderate dementia. However, there is little guidance on how to maximise cognition for severe dementia. Advanced Cognitive Stimulation Therapy (ACST) will be the first evidence-based complex intervention for moderate to severe dementia developed within the Medical Research Council (MRC) framework and building upon CST's key principles. This feasibility randomised controlled trial (RCT) aims to 1) evaluate the feasibility of ACST 2) explore if ACST can improve the cognitive function, and QoL, as well as other outcomes including behaviour, engagement, and communication, for people with moderate to severe dementia. A sample of 32 participants will be recruited, where 16 will be randomly allocated to ACST, and 16 to treatment as usual (TAU). Data will be collected pre and post the 7-week intervention period. Improving cognition and QoL for people with moderate to severe dementia is vital because dementia's prevalence is projected to reach 152 million by 2050, resulting in excessive excess disability. ;

Related Conditions & MeSH terms

• Alzheimer Disease
• DEM
• Dementia
• Dementia Frontal
• Dementia Moderate
• Dementia of Alzheimer Type
• Dementia Severe
• Dementia With Lewy Bodies
• Dementia, Mixed
• Dementia, Vascular
• Lewy Body Disease

• NCT number: NCT04550975
• Study type: Interventional
• Source: University College, London
• Contact: Esther K Hui, BSc
• Phone: +447460285290
• Email: esther.hui.19@ucl.ac.uk
• Status: Not yet recruiting
• Phase: N/A
• Start date: March 1, 2021
• Completion date: March 1, 2023