Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)

Dementia Clinical Trial

— MoCA-Norm  

Official title:

Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03246269
• Other study ID #: MoCA-Norm
• Status: Completed
• Start date: December 2016
• Est. completion date: April 2017

Study information

• Verified date: May 2018
• Source: University Hospital, Basel, Switzerland
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This observational cohort study in healthy volunteers establishes normative data for the German version of the Montreal Cognitive Assessment (MoCA) and investigates the possible impacts of demographics on the MoCA total score.

Description:

The Montreal Cognitive Assessment (MoCA) is a short tool to evaluate a multitude of cognitive domains (visuospatial / executive functioning, object naming, memory, attention, language, abstraction, orientation). The original English MoCA consistently showed very high sensitivity and specificity in distinguishing patients with mild cognitive impairment from healthy controls. Therefore it is an excellent tool for early recognition of cognitive disorders. Based on a Canadian sample, the MoCA proposes a cut-off-value of 26/30 points. However, there is increasing evidence of intercultural differences in terms of the best cut-off-score. In addition the original version only slightly corrects for possible influences of education - an adjustment for age- or gender-related effects is missing. Therefore, the aim of our study was to investigate the possible impacts of demographics on the MoCA total score and to provide normative values for a German-speaking population.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 334
• Est. completion date: April 2017
• Est. primary completion date: April 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Age =65 years

• Education =7 years

• Fluency in the German language

• Written informed consent

Exclusion Criteria:

• History of cognitive impairment

• Depression

• Severe sensory or motor impairment interfering with cognitive testing

• Serious somatic disease

• Disease or event affecting the central nervous system

• Cerebrovascular disease

• Regular medication with psychoactive drugs except for benzodiazepines

• Participation in a cognitive study within the last 3 months

Related Conditions & MeSH terms

• Alzheimer Disease
• Cognition Disorders
• Cognition Disorders in Old Age
• Cognitive Abnormality
• Cognitive Change
• Cognitive Decline
• Cognitive Deterioration
• Cognitive Dysfunction
• Cognitive Impairment
• Cognitive Impairment, Mild
• Cognitive Symptom
• Dementia
• Dementia Alzheimers
• Dementia of Alzheimer Type
• Dementia, Alzheimer Type
• Dementia, Mild
• Disease
• Neurobehavioral Manifestations

Intervention

Diagnostic Test:
• MoCA

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Andreas Monsch

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Montreal Cognitive Assessment (MoCA) - German version	Total score of the MoCA	Baseline
Secondary	Mini-Mental State Examination (MMSE)	Total score of the MMSE	Baseline
Secondary	Geriatric Depression Scale (GDS)	Total score of the GDS	Baseline
Secondary	Consortium to Establish a Registry for Alzheimer's Disease - Neuropsychological Assessment Battery (CERAD-NAB)	Total score of the CERAD-NAB	Baseline