Maximizing Independence at Home (MIND at Home)

Dementia Clinical Trial

Official title:

Maximizing Independence at Home (MIND at Home): Dementia Care at Home Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01283750
• Other study ID #: NA_00012829
• Secondary ID: 90032824
• Status: Completed
• Phase: Phase 2/Phase 3
• Start date: July 2008
• Est. completion date: December 2012

Study information

• Verified date: November 2018
• Source: Johns Hopkins University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Funded by a unique private philanthropy and public coalition through THE ASSOCIATED: Jewish Community Federation of Baltimore, this project seeks to develop effective ways to deliver dementia care to older adults with memory disorders who live in the community. MIND at Home is an 18 month intervention research study whose goals are two-fold: To partner with community organizations to help proactively identify older adults in the Baltimore community who may need help related to memory disorders; To find out if providing person-centered, coordinated care will help older adults with memory disorders remain at home longer, as well other possible benefits. The investigators hypothesize that individuals with memory disorders that receive person-centered, coordinated care will have fewer unmet dementia-related needs, improved quality of life and function, fewer behavioral and depressive symptoms, and will be able to remain in their homes longer compared to individuals who receive augmented usual care.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 303
• Est. completion date: December 2012
• Est. primary completion date: December 2011
• Accepts healthy volunteers: No
• Gender: All
• Age group: 70 Years and older

Eligibility

Inclusion Criteria:

• 70+ years old

• Community living (within one of 28 zip codes in Baltimore)

• Has memory disorder

• Has identified study partner willing to participate

• English-speaking

Exclusion Criteria:

• Situation at the time of referral is an emergency with risk of danger to individual or others

• Presence of delirium or other rule outs for memory disorder

Related Conditions & MeSH terms

• Dementia
• Memory Disorders

Intervention

Behavioral:
• care coordination
dementia-related care coordination

Locations

Country	Name	City	State
United States	Johns Hopkins University	Baltimore	Maryland

Sponsors (14)

Lead Sponsor

Collaborator

Johns Hopkins University

Baltimore County Department of Aging, Hirschhorn Foundation, Hoffberger Foundation, Jewish Community Federation of Baltimore, Jewish Community Services, Joseph and Harvey Meyerhoff Family Charitable Funds, Leonard & Helen R. Stulman Charitable Foundation, Levindale, Lois and Irving Blum Foundation, National Institute of Mental Health (NIMH), National Institute on Aging (NIA), The Harry & Jeanette Weinberg Foundation, Inc., The Henry and Ruth Blaustein Rosenberg Foundation

Country where clinical trial is conducted

United States, 

References & Publications (6)

Black BS, Johnston D, Morrison A, Rabins PV, Lyketsos CG, Samus QM. Quality of life of community-residing persons with dementia based on self-rated and caregiver-rated measures. Qual Life Res. 2012 Oct;21(8):1379-89. doi: 10.1007/s11136-011-0044-z. Epub 2 — View Citation

Black BS, Johnston D, Rabins PV, Morrison A, Lyketsos C, Samus QM. Unmet needs of community-residing persons with dementia and their informal caregivers: findings from the maximizing independence at home study. J Am Geriatr Soc. 2013 Dec;61(12):2087-95. — View Citation

Johnston D, Samus QM, Morrison A, Leoutsakos JS, Hicks K, Handel S, Rye R, Robbins B, Rabins PV, Lyketsos CG, Black BS. Identification of community-residing individuals with dementia and their unmet needs for care. Int J Geriatr Psychiatry. 2011 Mar;26(3):292-8. doi: 10.1002/gps.2527. Epub 2010 Jul 23. — View Citation

Marquardt G, Johnston D, Black BS, Morrison A, Rosenblatt A, Lyketsos CG, Samus QM. A Descriptive Study of Home Modifications for People with Dementia and Barriers to Implementation. J Hous Elderly. 2011 Jan 1;25(3):258-273. — View Citation

Marquardt G, Johnston D, Black BS, Morrison A, Rosenblatt A, Lyketsos CG, Samus QM. Association of the spatial layout of the home and ADL abilities among older adults with dementia. Am J Alzheimers Dis Other Demen. 2011 Feb;26(1):51-7. doi: 10.1177/153331 — View Citation

Samus QM, Johnston D, Black BS, Hess E, Lyman C, Vavilikolanu A, Pollutra J, Leoutsakos JM, Gitlin LN, Rabins PV, Lyketsos CG. A multidimensional home-based care coordination intervention for elders with memory disorders: the maximizing independence at ho — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in unmet dementia-related needs from Baseline to 18 months	Unmet dementia-related needs as measured by the Johns Hopkins Dementia Care Needs Assessment (JHDCNA), clinican-based assessment of 21 domains (92 individual items)	18 months
Secondary	Change in quality of life from Baseline to 18 months	Participant quality of life measured by Quality of Life in Alzheimers Disease (QOL-AD) and Alzheimer's Disease Related Quality of life scale (ADRQL). Caregiver quality of life measured by SF-12.	18 month
Secondary	length of stay	Length of stay in the community assessed by number of days from initial study assessment to end of study observation or to date that the subject leaves their community-based residence (e.g. move to nursing home, assisted living, death) prior to end of study observation.	18 months
Secondary	neuropsychiatric behavior symptoms from baseline to 18 months	Neuropsychiatric behavior measured by the Neuropsychiatry Inventory Questionnaire	18 month
Secondary	day-to-day function from baseline to 18 months	Day-to-day function assessed by the Instrumental Activities of Daily Living Scale and the Psycho-geriatric Dependency Rating Scale	18 month
Secondary	health care utilization from baseline to 18 months	Inpatient, residential, Alzheimer Disease-related, mental health, and medical health care use measured by the SURFS	18 month
Secondary	depression from baseline to 18 months	Participant depression measured by the Cornell Scale for Depression (CSDD) in Dementia. Caregiver depression measured by the Geriatric Depression Scale (GDS).	18 month

External Links

•   Johns Hopkins University press release (2/10/14)