Delirium Clinical Trial
Official title:
Non Invasive Monitoring of Cerebral Blood Flow During and After Cardiopulmonary Bypass to Assess and Compare for the Presence of Delirium in Post Operative Patients (DELIRIUM)
Cardiac surgery is associated with multiple events and issues that increase risk for adverse postoperative neurological outcomes including postoperative cognitive dysfunction. The risk for postoperative delirium is generally thought to result from some previous health factors added to the susceptibility of the cardiac surgery process.
Cardiac surgery is associated with multiple perturbations that increase risk for adverse
postoperative neurological outcomes including postoperative cognitive dysfunction. These
same perturbations likely also increase the risk for postoperative delirium although there
are little data that have evaluated this hypothesis.
As the subject is prepared for surgery 2 contact probes will be placed on the forehead to
monitor the rSO2 and cerebral blood flow. This monitor can also measureblood flow velocity
in blood vessels in the forehead.
This will only be done while the subject is on the cardiac bypass machine during the surgery
and end shortly after entering the intensive care unit.Prior to surgery and then once a day
on three of the first four postoperative days, patients will be assessed for the presence
and severity of delirium with brief standard psychological exams. We will compare rSO2 and
CBF changes between patients with and without delirium
;
Observational Model: Case Control, Time Perspective: Cross-Sectional
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