Delirium Clinical Trial
Official title:
A Prospective, Multi-centre, Randomised, Double-blind, Placebo-controlled Comparison of Intravenous Dexmedetomidine and Haloperidol in Treatment of Psychomotor Confusion After Heart Surgery
Primary hypothesis: Dexmedetomidine is equal or superior to haloperidol and placebo in the
treatment of psychomotor confusion in patients who are recovering from heart surgery.
Study design:
Multi-centre, prospective, randomised, placebo-controlled double-blind study of
dexmedetomidine vs. haloperidol for treatment of psychomotor confusion after cardiac
surgery. Data will be analyzed in two steps: The primary comparison is between placebo and
dexmedetomidine. If the effect of dexmedetomidine is significant, a secondary comparison
between dexmedetomidine and haloperidol will follow.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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