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Safety and Efficacy of Combined Sedation With Midazolam and Dexmedetomidine in ICU Patients

Delirium Clinical Trial

Official title:
Safety and Efficacy of Combined Sedation With Midazolam and Dexmedetomidine in ICU Patients

Clinical Trial Summary

It is well known that ICU patients need sedation. Now no ideal sedation drug existed and every sedation drug has its advantage and disadvantage,so combined sedation may use the advantage and avoid the disadvantage of the sedation drug according to the patients'condition. Until now, there is rare study about the combined sedation or sequenced sedation of different sedation drug.The purpose of the study is to explore the value of combined sedation with midazolam and dexmedetomidine compared to single drug sedation in ICU, so as to seek an ideal sedation protocol that could reduce the cost of treatment,obtain the appropriate sedation not under sedation or over sedation,reduce the incidence of delirium, reduce the adverse event of sedation.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02080169
Study type Interventional
Source Qilu Hospital
Contact
Status Recruiting
Phase Phase 4
Start date February 2014
Completion date December 2014
View Details
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