Dehydration Clinical Trial
Official title:
Hydration Amongst Nurses and Doctors Oncall
The main purpose of this study is to assess and compare the hydration status of medical and
nursing staff and to investigate the relationship between the hydration status, cognitive
function and serum cortisol (marker of stress).
We hypothesise that a significant proportion of doctors and nurses will be dehydrated at the
end of their working day. Some, as in other occupations, may be dehydrated at the start of
their working day. This is likely to be associated with impairment in cognitive performance
at the end of the working day compared to the beginning and expected to be more pronounced
after a night shift. There may be less noticeable difference amongst nursing staff given the
protected break time. Dehydration and associated impairment in cognition is of important
clinical value as it can impact patient care. participants will be involved in the study for
two shifts (one day and one night), aiming at 15 medical and 15 surgical nurses as well as
15 medical (total 15 day and 15 night shifts from each group) and surgical doctors (total 15
day and 15 night shifts from each group). Those that do not work both day and night shifts
will participate for only one shift and a new participant will be recruited until target
number of shifts is achieved.
End points
1. To assess the hydration status of hospital staff nurses and doctors oncall at work by
measuring the following:
1. Urine and serum osmolality
2. Urine mass produced during the shift
3. Kidney function (U &Es)
4. Bioimpedance measures
2- To assess the effect of hydration on status of cognitive function and
subjective feelings.
3- To assess the association between hydration status on stress hormone (cortisol)
levels.
Inclusion criteria All medical and nursing staff working on acute medical and
surgical admissions at the Queens Medical Centre Nottingham.
Exclusion Criteria:
Pregnancy Pre-existing kidney disease Patients on diuretics Unwell in the past 6
week with acute illness that warrants hospital admission or prescribed medication.
;
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