Craving & Decision-Making

Status Recruiting

Clinical Trial Summary

Craving is the strong desire for something, such as for substances in drug addiction and food or other activities in everyday life. Recent work suggests craving can influence how people make decisions and assign value to choice options available to them, yet the neural mechanisms underlying these interactions between craving and valuation remain unknown. To address this, this study uses cognitive decision-making tasks that measure how much individuals will pay (from a study endowment) to have everyday consumer items or snack foods when they crave something specific (opioids or a specific snack, respectively). First, the study will identify the neural mechanisms for how drug craving (craving for opioids) interacts with valuation for consumer items that have associations with drug use or not in people receiving treatment for opioid use disorder (OUD). This will be evaluated in the activity patterns and interactions among brain regions involved in craving and value assignment during decision-making. Then, the study will examine for parallel mechanisms for how food craving (craving for a specific snack) interacts with valuation for snack food items that have similar features to the craved snack or not in people receiving treatment for OUD and non-psychiatric community control participants.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Decision Making

Clinical Trial Details

NCT number	NCT06440577
Study type	Interventional
Source	Rutgers, The State University of New Jersey
Contact	Anna Konova, PhD
Phone	732-235-4335
Email	anna.konova@rutgers.edu
Status	Recruiting
Phase	N/A
Start date	June 2024
Completion date	December 2026

View Details

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