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Deafness clinical trials

View clinical trials related to Deafness.

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NCT ID: NCT01727492 Recruiting - Clinical trials for Noise-induced Hearing Loss

Prevention of Noise-induced Damage by Use of Antioxidants

Start date: November 2012
Phase: N/A
Study type: Interventional

The current study is a dubble-blinde placebo-controlled cross-over study verifying the preventive effect of antioxidants on noise-induced hearing loss (NIHL) and noise-induced tinnitus (NIT). The antioxidants comprise of a mixture of magnesium and n-acetylcystein which should be taken 1h before leisure noise above 100dB for at least 30 minutes.

NCT ID: NCT01715948 Completed - Unilateral Deafness Clinical Trials

Comparison of BAHA and CROS Hearing Aid in Single-Sided Deafness

Start date: January 2013
Phase: N/A
Study type: Interventional

People with single-sided deafness (SSD) have significant hearing loss in one ear and normal or near normal hearing in the other ear. Those living with SSD experience several communication difficulties, particularly when listening to speech in the presence of background noise. This problem is worse in situations where the noise is on the side of the good ear and the speech is on the side of the poor ear. The Bone-Anchored Hearing Aid (BAHA) and the Contralateral Routing of Signals (CROS) hearing aid are two devices designed to improve hearing in people who have significant hearing loss in one ear only. The BAHA is a surgically implanted device which also includes an external processor; sounds from the poor ear are transmitted to the good ear through skull vibrations. The CROS does not involve surgery; instead a hearing aid is fitted behind each ear, and the sounds on the side of the poor ear are wirelessly transmitted to the good ear. The majority of previous studies comparing the BAHA to the CROS have used older CROS models with basic technology and a wire along the neck to send sounds from the poor ear to the good ear. There is a lack of studies comparing newer digital wireless CROS hearing aids to the BAHA. The current research will compare the effect of the BAHA and CROS hearing aid on speech perception scores when listening to speech in quiet and in noise. The research will also investigate patients' reported benefits with each device during everyday situations. In order to compare the BAHA and CROS, individuals who already have been implanted with a BAHA will be given a trial period with a new wireless digital CROS hearing aid. The research hypothesis states that the CROS hearing aid will be as equally beneficial or greater than the BAHA in improving hearing and patient benefit. If the findings support the hypothesis that the CROS offers just as much benefits as the BAHA, or is an even better alternative, more patients may choose to avoid surgery and decide to receive a CROS hearing aid instead.

NCT ID: NCT01714375 Completed - Hearing Loss Clinical Trials

Daily Exposure Monitoring to Prevent Hearing Loss

DEMON
Start date: July 1, 2007
Phase: N/A
Study type: Interventional

The goal of this study is to determine whether daily assessment and feedback of workers' noise exposures leads to more effective use of hearing protection and prevention of noise-induced hearing loss.

NCT ID: NCT01671176 Completed - Clinical trials for Conductive Hearing Loss

Wide Diameter Bone Anchored Implant Study

Start date: May 2012
Phase: N/A
Study type: Interventional

To assess implant stability, implant loss, adverse skin reactions, and Quality of Life Benefit following implantation of the Ponto 4.5mm Wide Diameter implant. Secondary: to determine the feasibility of fitting the sound processor 3 weeks after surgical implantation, and to investigate if the type of skin reactions following implantation could be related to the demographic data of subjects and the type of surgical technique used

NCT ID: NCT01670006 Completed - Clinical trials for Single Sided Deafness

Implantation of the Cochlear® Nucleus® System in Adults With Single-Sided Deafness

Start date: October 2012
Phase: N/A
Study type: Interventional

The objective of this feasibility study is to obtain preliminary safety and efficacy data associated with cochlear implantation in individuals with severe to profound sensorineural hearing loss contralateral to an ear with normal, or near-normal, hearing. The hypothesis is that restoration of hearing in the deafened ear will result in improved speech perception in the treated ear and advantages related to restoration of hearing to both ears.

NCT ID: NCT01655212 Terminated - Clinical trials for Sensorineural Hearing Loss

Congenital Cytomegalovirus: Efficacy of Antiviral Treatment in a Randomized Controlled Trial

CONCERT
Start date: June 2012
Phase: Phase 3
Study type: Interventional

The objective of the trial is to investigate whether early treatment with oral valganciclovir of infants with both congenital cytomegalovirus infection and sensorineural hearing loss can prevent progression of hearing loss.

NCT ID: NCT01649869 Completed - Clinical trials for Cytomegalovirus Infection

Valganciclovir Therapy in Infants and Children With Congenital CMV Infection and Hearing Loss

Start date: February 24, 2015
Phase: Phase 2
Study type: Interventional

This is an international, multi-center, double-blind, placebo-controlled evaluation valganciclovir treatment for up to 54 children (up to 4 years of age) with virologically-confirmed congenital CMV infection and hearing loss. Subject participation will be over a six-month period and study subjects will be stratified according to age. The primary objective is to assess whether a six-week course of oral valganciclovir can stabilize the hearing of children with congenital CMV infection who present with hearing loss.

NCT ID: NCT01621256 Completed - Hearing Loss Clinical Trials

Efficacy, Safety, and Tolerability of Ancrod in Patients With Sudden Hearing Loss

Start date: May 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether ancrod is effective and safe in the treatment of sudden sensorineural hearing loss (SSHL).

NCT ID: NCT01620385 Recruiting - Hearing Impaired Clinical Trials

Cochlear Implant PDA Based Research Platform

ciPDA
Start date: June 2011
Phase: Phase 1
Study type: Interventional

The primary purpose of the research is to study how individuals who wear cochlear implants process sounds in noisy environments and also whether newly designed programs can help improve the communicative ability of cochlear implant patients in noisy situations.

NCT ID: NCT01611129 Completed - Clinical trials for Disability Evaluation

Internet-based Pre-fitting Counseling of Persons With Hearing Impairment

Start date: November 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the use of 'patient journey' model in internet-based counseling of a person with hearing impairment is a feasible approach in management of emotional and social consequences, anxiety and depression, readiness to change and acceptance of hearing loss.