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Deafness clinical trials

View clinical trials related to Deafness.

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NCT ID: NCT03902093 Withdrawn - Hearing Loss Clinical Trials

Morphology Effects of Extended Wear Hearing Instrument

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The lyric hearing device is a commercially available device produced by Sonova, and designed to be used for extended periods of time. We further want to investigate the morphology of the tissue around the device at different periods of time after the device has been fitted and used for a while. An initial imaging of the tissue will be taken for baseline measurements. Questionnaires will also be used to assess patients satisfaction with the device and cognitive abilities.

NCT ID: NCT03895333 Completed - Hearing Loss Clinical Trials

Hearing Loss and Osteoporosis

Start date: March 1, 2019
Phase:
Study type: Observational

To compare the audiological profiles in postmenopausal women with and without osteoporosis and to examine the pattern of hearing loss in osteoporotic patients. postmenopausal women will be separated as normal, osteopenic and osteoporotic according to bone mineral densitometry results. The evaluation of hearing test will be done in these groups and the results will be compared between the groups.

NCT ID: NCT03892941 Recruiting - Deafness Clinical Trials

Electric Pace-pitched Hearing Achieves Natural Tonotopy

ELEPHANT
Start date: March 18, 2019
Phase: N/A
Study type: Interventional

In search of the best possible outcome for the severe hearing impaired who have regained the ability to hear by means of a cochlear implant (CI), electrical stimulation and the information it carries should match as closely as possible to what the human brain naturally has evolved to cope with and learned to process instead of relying on plasticity to adapt to an induced mismatch. At the moment, however, CI's are fitted with a 'one size fits all' principle. This is known to cause a mismatch between the frequencies presented by the CI electrode array and the frequencies represented at the corresponding natural acoustic location in an individual cochlea. In this study it is hypothesized that an individual imaged based fitting that pursues natural hearing alignment and is implemented from the start of the rehabilitation process, will improve the individual outcomes of electric hearing. The natural fitting strategy is thought to give rise to a steeper learning curve, result in a better performance in challenging listening situations, improve sound quality, complement better with residual acoustic hearing in the contralateral ear and win the preference of CI-recipients.

NCT ID: NCT03872882 Completed - Hearing Loss Clinical Trials

Accuscreen Equipment Evaluation For Newborn Hearing Screening

Start date: March 22, 2017
Phase:
Study type: Observational

An evaluation and comparison of results between the 'Accuscreen New' currently in use and an 'Accuscreen New' with different settings to see if the new settings reduce unnecessary referrals for babies from newborn hearing screening. Babies will be tested with the standard and modified equipment. Referrals for diagnostic testing will be based on the standard equipment. A comparison in referrals between the standard and modified equipment will be made.

NCT ID: NCT03870217 Terminated - Deafness Clinical Trials

Comparing Site-selection Strategies

Start date: August 1, 2020
Phase:
Study type: Observational

Several studies in the past have tried to deactivate electrodes that are less optimal to improve speech recognition outcomes. The study aims to compare the measures based on which the deactivation was performed. The investigators aim to first examine if the measures are strongly correlated each other, and then compare the deactivation effects across measures. These measures are mainly behavioral including electrode discrimination, amplitude modulation detection thresholds, low-rate and focused detection thresholds and electrode-modiolus distance. The endpoint of the study is speech recognition performance post deactivation.

NCT ID: NCT03867396 Completed - Clinical trials for Hearing Loss, Sensorineural

Evaluation of Speech-in-noise Performance in Cochlear Implant Recipients With a CROS Device on the Contralateral Ear

Start date: January 23, 2019
Phase: N/A
Study type: Interventional

Speech understanding in noise remains the greatest challenge for people using cochlear implants, particularly when the speech of interest comes from the side of the head opposite to the implant. Recent findings in hearing technology allow for people to either use a hearing aid or a Contralateral Routing of Signal (CROS) device on the non-implanted ear. Differences in speech understanding may result depending on the device chosen by a person, and these differences may be measureable through speech discrimination measurement methods. This study intends to determine whether or not a CROS device improves speech perception in noise when the source of the speech of interest originates from the side of the head opposite to the implant.

NCT ID: NCT03867058 Terminated - Deafness Clinical Trials

Tradeoff Between Spatial and Temporal Resolution

Start date: October 1, 2019
Phase:
Study type: Observational

In this study, investigators will examine how temporal rate processing might be affected when the width of neural excitation narrows. The manipulation of neural excitation width will be achieved for example by changing electrode configurations or stimulating single versus multiple electrodes simultaneously. Investigators will then measure if the extent to which rate processing is affected by spatially restricted stimulation can predict a subject's overall speech recognition and predict also whether the subject is likely to benefit from a focused electrode configuration. Lastly, investigators will introduce and test a novel current focusing strategy where current focusing is applied in a channel specific manner and quantify if this intervention improves speech recognition. The primary endpoint of the study is speech recognition, and the secondary endpoint is psychophysical sensitivity to stimulation rate change.

NCT ID: NCT03867032 Withdrawn - Deafness Clinical Trials

Auditory Training With Speech Related Acoustic Cues Using Psychophysical Testing

Start date: December 2022
Phase: N/A
Study type: Interventional

In this study, the investigators will evaluate whether auditory training with speech-related acoustic features in psychophysical testing will help CI subjects improve speech recognition. The primary endpoint is the speech recognition measures.

NCT ID: NCT03866850 Terminated - Congenital Deafness Clinical Trials

Degenerative Consequences of Congenital Deafness

Start date: August 1, 2019
Phase:
Study type: Observational

In this study, the investigators will study one of the basic biophysical properties of the auditory nerve, charge integration, behaviorally (detection threshold versus phase duration functions). The investigators will compare charge integration in two subject groups: congenitally deafened and deafened at a later age in life. The investigators will then examine if behaviorally estimated neural excitation patterns differ between short phase duration and long phase duration stimulation. Lastly, The investigators will measure if speech recognition improves with using long phase duration stimulation, relative to using the standard default short phase duration stimulation. The primary endpoint of the study is speech recognition, and the secondary endpoints are the steepness of the detection threshold versus phase duration functions, and the width of psychophysically estimated neural excitation.

NCT ID: NCT03866460 Active, not recruiting - Hearing Loss Clinical Trials

Determining Whether Intra-Arterial Carboplatin Causes Hearing Loss in Children

Start date: March 6, 2019
Phase:
Study type: Observational

The purpose of this study is to find out how often hearing loss occurs in patients with retinoblastoma after receiving treatment with intra-arterial carboplatin.