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Clinical Trial Summary

Ophthalmological screening for cytomegalovirus retinitis (CMVR) for HIV/AIDS patients is important. However, the manual screening with fundus imaging is laborious and subjective. Deep learning (DL) system has been developed for the automated detection of various eye diseases with high accuracy and efficiency, including diabetic retinopathy, glaucoma, age-related macular degeneration (AMD), papilledema, lattice degeneration and retinal breaks, from ocular fundus photographs. UWF imaging is a relatively new imaging modality for DL system but has also shown extraordinary talents in automatic retinal analysis With the press for routine CMVR screening in AIDS patients and the great capacity of DL system, the use of deep learning (DL) system to AIDS-related CMVR with Ultra-Widefield (UWF) fundus images is promising. The investigators previously developed a DL system to detect AIDS-related CMVR. For further evaluating the applicability of the DL system, a prospective dataset is needed.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04831333
Study type Observational [Patient Registry]
Source Beijing YouAn Hospital
Contact
Status Completed
Phase
Start date April 1, 2021
Completion date May 1, 2021

See also
  Status Clinical Trial Phase
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Completed NCT01866397 - Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration Phase 4
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Completed NCT00000136 - Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) Phase 3
Completed NCT00091884 - Efficacy of Elevated CD4 Counts on CMV Retinitis N/A
Recruiting NCT05911503 - Clinical Study of High Concentration Ganciclovir Eye Drops in the Treatment of Cytomegalovirus Retinitis Early Phase 1
Completed NCT00002377 - A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes Phase 3
Completed NCT00001611 - Immune Activity Against CVM Retinitis N/A
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Completed NCT00000168 - Longitudinal Study of Ocular Complications of AIDS (LSOCA) N/A
Active, not recruiting NCT00002384 - A Study of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS N/A
Active, not recruiting NCT00017784 - Valganciclovir in Patients With CMV Retinitis and AIDS Who Cannot Take Drugs by Injection Phase 3
Active, not recruiting NCT00002301 - A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir N/A
Completed NCT00002034 - A Study of the Safety and Tolerance of Long-Term Therapy With Intravenous Cytovene (Ganciclovir Sodium) for Cytomegalovirus Retinitis in Persons With AIDS N/A
Completed NCT00002156 - A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR ) Phase 2
Completed NCT00002039 - An Open Study of Foscarnet Treatment First Episode CMV-Retinitis in AIDS Patients N/A
Completed NCT00002142 - An Open-Label Study of the Safety and Efficacy of Cidofovir for the Treatment of Relapsing Cytomegalovirus Retinitis in Patients With AIDS N/A