Cystitis, Interstitial Clinical Trial
Official title:
Efficacy of DMSO Cocktail Treatment in Interstitial Cystitis Patients During and After Treatment
The purpose of this study is to examine the efficacy of dimethylsulphoxide (DMSO) cocktail in patients with interstitial cystitis during the treatment period (12 weeks) and after it (at 6 weeks, 3, 6 and 12 month).
The modern treatment of IC is a multi-modal treatment which includes behavioural treatment,
physiotherapy of the pelvic floor musculature, oral medication (e.g. Amitryptiline) and
intra-vesical instillation (e.g. DMSO, steroids, heparin). These treatments were found to be
effective in a number of studies and are approved by the FDA. However, the optimal duration
of intra-vesical instilation is not known.
All patients with IC (according to the international continence society criteria) will
receive 12 weekly intra-vesical instillation of DMSO. All patients will fill an O'leary-Sant
questionaire and a urination diary before treatment, after 3, 6, 9 and 12 treatments and at
6 weeks, 3, 6 and 12 month after the end to the treatment.
;
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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