Acceleration of Lower Anterior Teeth Leveling and Alignment Using Corticision

Crowding, Tooth Clinical Trial

Official title:

Evaluation of the Efficiency of Corticision on Accelerating of Leveling and Alignment Lower Crowded Incisors Using Cone Beam Computed Tomography - A Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03310086
• Other study ID #: UDDS-Ortho-07-2017
• Status: Completed
• Phase: N/A
• Start date: January 2017
• Est. completion date: July 15, 2018

Study information

• Verified date: July 2018
• Source: Damascus University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This experimental study will evaluate the effect of corticision on accelerating the leveling and alignment of lower crowded incisors compared with the control untreated group using cone beam computed tomography.

The study sample will consist of 26 patients with less than 6 mm crowding. The sample will be allocated randomly into two experimental groups.

The brackets and passive SS wire will be applied with radiographic metal guides between each tooth to allow for accurate corticision site 2 mm below the gingival papilla and to prevent tooth roots injury. The dentoalveolar changes occurring after leveling and alignment of lower anterior teeth will be evaluated using CBCT radiographs, Frequency, degree of root resorption, and the incidence of bone dehiscence will be assessed in relation to initial situation.

Description:

Crowding is the most common form of malocclusion. Different methods have been used to resolve crowding, including extraction and nonextraction. Corticision is an important methods to accelerate tooth movement in crowded cases. Cortical bone incision without flap elevation enhances turnover rate of surrounding structures and decreases the time for leveling and alignment. In orthodontics, CBCT imaging has been applied to evaluate impacted teeth and root resorption. But the data are very rare regarding the application of CBCT in tooth movement. So CBCT will be used in this research to evaluate the amount of external apical root resorption (EARR) and presence of dehiscence in the lower anterior teeth in the crowded cases. Furthermore, the duration of alignment will be compared between corticision group and non-corticision group.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 26
• Est. completion date: July 15, 2018
• Est. primary completion date: December 20, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 25 Years

Eligibility

Inclusion Criteria:

• patients age 18 years or more

• complete permanent dentition with second molars

• crowding of less than 6 mm

• good healthy patients without systematic diseases

• absence of spaces in the lower dental arch

• orthodontic treatment protocol does not required extraoral appliances, intraoral elastics, and expansion during leveling and alignment in the lower arch

• good oral hygiene

• absence of periodontal lesion

Exclusion Criteria:

• patients with syndromes, clefts, or craniofacial abnormalities or systematic diseases

• poor oral hygiene or periodontal lesion

• previous orthodontic treatment.

• Inability for brackets bonding in lower anterior teeth

• presence of extreme skeletal discrepancy in vertical , transverse and anteroposterior relations

• Delay rebonding of any loosing brackets for more than one week in the lower anterior teeth

Related Conditions & MeSH terms

• Crowding, Tooth
• Malocclusion

Intervention

Device:
• Traditional fixed appliance
aligning and leveling of lower anterior teeth using traditional fixed appliance.

Procedure:
• Corticision
Corticison, cortical bone incision without flap elevation, will be applied to the lower anterior teeth

Locations

Country	Name	City	State
Syrian Arab Republic	Damascus University	Damascus

Sponsors (1)

Lead Sponsor	Collaborator
Damascus University

Country where clinical trial is conducted

Syrian Arab Republic, 

References & Publications (6)

Alikhani M, Raptis M, Zoldan B, Sangsuwon C, Lee YB, Alyami B, Corpodian C, Barrera LM, Alansari S, Khoo E, Teixeira C. Effect of micro-osteoperforations on the rate of tooth movement. Am J Orthod Dentofacial Orthop. 2013 Nov;144(5):639-48. doi: 10.1016/j — View Citation

Castro IO, Alencar AH, Valladares-Neto J, Estrela C. Apical root resorption due to orthodontic treatment detected by cone beam computed tomography. Angle Orthod. 2013 Mar;83(2):196-203. doi: 10.2319/032112-240.1. Epub 2012 Jul 19. — View Citation

Guo QY, Zhang SJ, Liu H, Wang CL, Wei FL, Lv T, Wang NN, Liu DX. Three-dimensional evaluation of upper anterior alveolar bone dehiscence after incisor retraction and intrusion in adult patients with bimaxillary protrusion malocclusion. J Zhejiang Univ Sci — View Citation

Mathews DP, Kokich VG. Accelerating tooth movement: the case against corticotomy-induced orthodontics. Am J Orthod Dentofacial Orthop. 2013 Jul;144(1):5-13. doi: 10.1016/j.ajodo.2013.04.008. — View Citation

Park YG. Corticision: A Flapless Procedure to Accelerate Tooth Movement. Front Oral Biol. 2016;18:109-17. doi: 10.1159/000351904. Epub 2015 Nov 24. — View Citation

Ponder SN, Benavides E, Kapila S, Hatch NE. Quantification of external root resorption by low- vs high-resolution cone-beam computed tomography and periapical radiography: A volumetric and linear analysis. Am J Orthod Dentofacial Orthop. 2013 Jan;143(1):7 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Speed of lower teeth movement.	The speed of lower teeth movement during leveling and alignment stage will be measured and compared between groups.	After the leveling and alignment stage of the lower teeth, which will take approximately 9 months
Secondary	Changes of lower teeth torque	The torque changes of the lower teeth will be evaluated and compared between the 2 groups using CBCT.	Changes will be evaluated before and after the lower teeth leveling and alignment stage, which will take approximately 8 months
Secondary	Changes of lower teeth tipping	The tipping changes of the lower teeth will be evaluated and compared between the 2 groups using CBCT.	Changes will be evaluated before and after the lower teeth leveling and alignment stage, which will take approximately 8 months