Cross-Sectional Study Clinical Trial
Official title:
The Impact of Pharmaceutical Medication Review, Medication Interview Before Discharge and Follow-up: A Randomized Controlled Trial
Verified date | November 2019 |
Source | Odense University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Background
It is well known that the transfer of a patient from hospital to the general practitioner is
related with mistakes in the medication of the patient. A report from 2006 measure the number
of drug related admissions in Denmark to be 69.000 to 162.000 per year. To reduce these
mistakes, more and better communication between the health professionals are suggested.
Furthermore medication reviews made by pharmacist seems to reduce the number of drug related
readmissions and other drug related issues, which can lead to an economic cost reduction.
Objective
The aim of this study is to investigate the impact of medication review and better
communication between the health professionals after discharge of a patient from hospital to
the general practitioner. The effect is measured as reducing the number of readmissions and
number of visits at the emergency department 30 days and six month after inclusion of the
patient.
Method
This study was estimated to include 1500 participants. The patients were randomized to one of
three groups; usual care, basic intervention or extended intervention. The usual care
received the normal care following the Danish standard procedure. The basic intervention had
a medication review by a clinical pharmacist during admission.
The extended interventions group was similar to the basic intervention group plus follow-up
with the patient, the general practitioner and if relevant the nursing home and pharmacy one
week and six month after discharge by interview with the clinical pharmacist.
Status | Completed |
Enrollment | 1499 |
Est. completion date | October 24, 2015 |
Est. primary completion date | April 24, 2015 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Usual medicine of five drugs or above - Speak and understand Danish - Admitted via the Acute Medicine Admission Ward - Are able to give informed consent Exclusion Criteria: - Patients included in a similar study - Declared terminal - Suicidal - In custody - Isolated at the hospital - Im- and/or expressive aphasia - Severe dementia |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Lene V. Ravn-Nielsen | The Actavis Foundation, The Hospitals Pharmacies’ and Amgros’ Research Development Foundation, Two public Regional foundations, University of Southern Denmark |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Readmissions | number of patients who have been readmitted | 30 days | |
Primary | Admissions | number of patients who have been admitted | 180 days | |
Primary | Emergency Department Visits | number of patients who have emergency department visits | 180 days | |
Primary | Composite Endpoint, Admissions or Emergency Department Visits | number of patients who experience primary composite endpoint, admissions or emergency department visits within 6 month | 180 days | |
Secondary | Drug-related Admissions | number of patients who have drug related admissions | 180 days after the inclusion date | |
Secondary | Drug-related Readmissions | number of patients who have drug related readmissions | 30 days after the inclusion date | |
Secondary | Percentage of Medication Changes Accepted by GPs | Acceptance rate in primary care (general practitioner). Medication review data were not collected from the Usual care Group and were collected only for the Basic and Extended Groups. | up to 180 days | |
Secondary | Medication Review Changes Accepted by Physicians (in Hospital) | Medication review data were not collected from the Usual care Group and were collected only for the Basic and Extended Groups. | 1 month | |
Secondary | Mortality | number of patient who died within 6 month after inclusion | 180 days after the inclusion date | |
Secondary | Drug Related Mortality | number of patients who have drug related death | 180 days after the inclusion date |
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