Crohn's Disease Clinical Trial
Official title:
A Phase II, Multi-Center, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, and Efficacy of Intravenous Antegren (Natalizumab) in Crohn's Disease Subjects Concurrently Receiving Remicade (Infliximab) and Not in Remission
The purpose of this study is to determine the safety, tolerability, and efficacy of
natalizumab in individuals diagnosed with active Crohn's Disease that are not in remission
(CDAI greater than/equal to 150) and are currently taking Remicade. It is thought that
natalizumab may stop the movement of certain cells, known as white blood cells, into bowel
tissue. These cells are thought to cause damage in the bowel leading to the symptoms of
Crohn's disease.
Patients who complete this study may be eligible for long-term natalizumab therapy via
extension protocol ELN100226-351.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment
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