Crohn's Disease Clinical Trial
Official title:
A Phase II, International, Multicenter, Open Label Study of the Safety, Tolerability and Effectiveness of Three Intravenous Infusions of Antegren (Natalizumab) in Adolescents With Moderately to Severely Active Crohn's Disease
The purpose of this study is to determine the safety and tolerability of natalizumab in
adolescents (ages 12-17) diagnosed with moderately to severely active Crohn's disease (CD).
It is thought that natalizumab may stop the movement of certain cells, known as white blood
cells, into bowel tissue. These cells are thought to cause damage in the bowel leading to
the symptoms of Crohn's disease.
Patients who complete this study may be eligible for long-term natalizumab therapy via
extension protocol ELN100226-352.
n/a
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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