Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease

Status Active, not recruiting

Clinical Trial Summary

This research study will evaluate if specific blood, stool and MRI tests can tell the difference between bowel wall inflammation without scarring and bowel wall inflammation with scarring that can cause bowel blockages requiring surgery.

Clinical Trial Description

This multi-center study will test the accuracy of individual and combined MRI and blood-based diagnostic tools in both children and adults with small bowel CD. We will determine the accuracy of a composite tool (including its multiple individual biomarkers) for defining the relative amounts of intestinal inflammation versus scarring in patients at the time of surgery (B2 disease) and in patients at an early stage of disease prior to complications (B1 disease). ;

Study Design

Related Conditions & MeSH terms

Crohn Disease

Clinical Trial Details

NCT number	NCT04088773
Study type	Observational
Source	Children's Hospital Medical Center, Cincinnati
Contact
Status	Active, not recruiting
Phase
Start date	November 1, 2019
Completion date	September 2024

View Details

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