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Iohexol Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance — GFR-ARC  

Critically Ill Clinical Trial

Official title:
Evaluation of Glomerular Filtration Rate Using Iohexol Plasma Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance

Clinical Trial Summary

Evaluation of glomerular filtration rate using iohexol plasma clearance in critically ill patients with augmented renal creatinine clearance

Clinical Trial Description

Single center study in ICU patients with augmented renal clearance comparing glomerular filtration rate (GFR) as measured by iohexol plasma clearance to that measured by creatinine clearance. Primary objective is to compare the GFR estimates made by iohexol plasma clearance (as reference method) and creatinine clearance using Bland-Altman method. Secondary objective are to compare GFR as measured by iohexol plasma clearance to that calculated with the most commonly used renal clearance estimating formulas (Cockcroft and Gault, MDRD and CKD-EPI ), evaluate clinical determinant of the observed differences and evaluate determinants of extracellular volume. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04776486
Study type Interventional
Source Assistance Publique - Hôpitaux de Paris
Contact Magalie Collet, MD
Phone +33 (0)149958515
Email magalie.collet@aphp.fr
Status Recruiting
Phase N/A
Start date September 3, 2020
Completion date March 2024
View Details
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