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Airway IgA: Respiratory Tract IgA Levels in Critically Ill Intubated Patients

Critically Ill Clinical Trial

Official title:
Respiratory Tract IgA Levels in Critically Ill Intubated Patients

Clinical Trial Summary

This study will examine the impact of acute illness on sequential airway IgA levels in intensive care patients who will require prolonged intubation. Infections are the most common cause of late deaths in non-head injured trauma patients and a frequent cause of morbidity and mortality in hospitalized patients, especially intubated Intensive Care Unit (ICU) patients. Nosocomial pneumonia is the most common of these infections, and its incidence in defined populations of critically injured patients is responsive to route and type of nutrition. This study will focus on the mechanisms of specific immune mucosal defenses in intestinal and extraintestinal sites and link enteral feeding (or lack of it) with maintenance (or deterioration) of respiratory mucosal defenses.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00205309
Study type Observational
Source University of Wisconsin, Madison
Contact
Status Completed
Phase N/A
Start date January 2003
Completion date June 2011
View Details
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