Clinical Trials Logo
  1. Home
  2. Critical Illness
  3. NCT04097210
  4. Details
NCT04097210 Clinical Trial

Decision-making - the Benefit of Bedside CRP Within Ambulance Care

Critical Illness Clinical Trial

— Q-CRP  

Official title:
When Triage is Insufficient - the Benefit of Bedside CRP Within Ambulance Care

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04097210
Other study ID # HUS 329/13/3/02/2015
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2016
Est. completion date June 1, 2021

Study information
Verified date November 2018
Source Helsinki University Central Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Patients with degreased (DGC) for ambiguous reasons receive low triage priority. Their death risk is triple. Tools are needed to identify the critically ill patients from this group. The triage used today is not effective. The bedside point-of-care measurements are CRP, lactate acid and suPAR (Soluble Urokinase Plasminogen Activator Receptor). Elevated values associate with the probability of critical illness and predict a risk of death.

Description:

Purpose: To improve identification and proper prioritization of patients with non-specific symptoms prehospitally, we intend to investigate whether Q-CRP, a rapid test for CRP, correlates with time-critical states in the above-mentioned patient group alone or together with CRP, lactate and suPAR. The primary endpoint is need for hospital care. Material: Patients over 18 years who exhibit non-specific symptoms and transported to the emergency room. Method: In patients with unspecified conditions, defined according to the inclusion template, a venous blood sample was taken prehospitally at the scene by the EMS. Analysis: Significance tests and regression analyzes with 95% CI were used. The diagnostic accuracy of Q-CRP, lactate, suPAR and combinations thereof were compared with optimal boundary values.

Recruitment information / eligibility
Status Completed
Enrollment 110
Est. completion date June 1, 2021
Est. primary completion date June 1, 2021
Accepts healthy volunteers
Gender All
Age group 16 Years to 104 Years
Eligibility Inclusion Criteria: - Patients over 18 years who exhibit non-specific symptoms and transported to the emergency room. Exclusion Criteria: - Abnormal vitals

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• POC

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Helsinki University Central Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary Number of patients with high suPAR level A high suPAR level, e.g. above 6 ng/ml 24 hours
See also
  Status Clinical Trial Phase
Completed NCT04551508 - Delirium Screening 3 Methods Study
Recruiting NCT06037928 - Plasma Sodium and Sodium Administration in the ICU
Completed NCT03671447 - Enhanced Recovery After Intensive Care (ERIC) N/A
Recruiting NCT03941002 - Continuous Evaluation of Diaphragm Function N/A
Recruiting NCT04674657 - Does Extra-Corporeal Membrane Oxygenation Alter Antiinfectives Therapy Pharmacokinetics in Critically Ill Patients
Completed NCT04239209 - Effect of Intensivist Communication on Surrogate Prognosis Interpretation N/A
Completed NCT05531305 - Longitudinal Changes in Muscle Mass After Intensive Care N/A
Terminated NCT03335124 - The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock Phase 4
Completed NCT02916004 - The Use of Nociception Flexion Reflex and Pupillary Dilatation Reflex in ICU Patients. N/A
Recruiting NCT05883137 - High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill
Completed NCT04479254 - The Impact of IC-Guided Feeding Protocol on Clinical Outcomes in Critically Ill Patients (The IC-Study) N/A
Recruiting NCT04475666 - Replacing Protein Via Enteral Nutrition in Critically Ill Patients N/A
Not yet recruiting NCT04516395 - Optimizing Antibiotic Dosing Regimens for the Treatment of Infection Caused by Carbapenem Resistant Enterobacteriaceae N/A
Not yet recruiting NCT04538469 - Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and Staff
Withdrawn NCT04043091 - Coronary Angiography in Critically Ill Patients With Type II Myocardial Infarction N/A
Recruiting NCT02922998 - CD64 and Antibiotics in Human Sepsis N/A
Recruiting NCT02989051 - Fluid Restriction Keeps Children Dry Phase 2/Phase 3
Completed NCT02899208 - Can an Actigraph be Used to Predict Physical Function in Intensive Care Patients? N/A
Completed NCT03048487 - Protein Consumption in Critically Ill Patients
Recruiting NCT02163109 - Oxygen Consumption in Critical Illness