Lactated Ringer's and PlasmaLyte in Critically Ill Adults

Critical Illness Clinical Trial

Official title:

Lactated Ringer's and PlasmaLyte in Critically Ill Adults

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03813563
• Other study ID #: RL vs Plalyte
• Status: Active, not recruiting
• Start date: January 13, 2018
• Est. completion date: February 2019

Study information

• Verified date: January 2019
• Source: West China Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In recent years, there has been a large amount of literature reports that normal saline can increase the incidence of renal injury in critically ill patients compared with balanced salt solution.However, no studies have compared the effects of different types of balanced salt solutions on the incidence of renal injury.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 12000
• Est. completion date: February 2019
• Est. primary completion date: December 15, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• All patients admitted to ICU

Exclusion Criteria:

• Patients <18 year old when admission

• Patients who stay less than 24 hours in ICU

• Patients who do not sufficient data for further analysis

• Readmission patients during the study period

Related Conditions & MeSH terms

• Critical Illness

Intervention

Drug:
• RL
lactated Ringer's
• PLA
PlasmaLyte

Locations

Country	Name	City	State
China	Department of Critical care medicine of West China Hospital	Chengdu	Sichuan

Sponsors (1)

Lead Sponsor	Collaborator
West China Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The incidence of acute kidney injury	The incidence of acute kidney injury	from admission to 28 days
Secondary	the incidency of CRRT events	the incidency of CRRT events	from admission to 28 days
Secondary	the ventilation free days	the ventilation free days	from admission to 28 days
Secondary	the vasopressure free days	the vasopressure free days	from admission to 28 days