Trace Element Repletion Following Severe Burn Injury

Status Completed

Clinical Trial Summary

Major burn patients are characterized by large exudative losses of Cu, Se and Zn. Trace element (TE) repletion has been shown to improve clinical outcome. The study aimed to check if our repletion protocols were achieving normalization of TE plasma concentrations of major burn patients and if the necessity for continuous renal replacement therapy (CRRT) might increase the needs.

Clinical Trial Description

Retrospective analysis of prospectively collected data in burn patients requiring intensive care (ICU) between 1999 and 2015. The cohort was divided into 4 groups according to the protocol changes. Period 1 (P1): 1999-2000, P2: 2001-2005, P3: 2006-2010, P4: 2011-2015. Changes consisted mainly in increasing TE repletion doses and duration. Demographic data, daily TE intakes and weekly plasma concentrations were retrieved for the first 21 ICU-days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03204669
Study type	Observational
Source	Centre Hospitalier Universitaire Vaudois
Contact
Status	Completed
Phase	N/A
Start date	June 1, 1999
Completion date	December 31, 2015

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