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Hyporesponsiveness of Natural Killer Cells and a Dysfunctional Inflammatory Response in Critically Ill Patients

Critical Illness Clinical Trial

Official title:
Hyporesponsiveness of Natural Killer Cells and a Dysfunctional Inflammatory Response in Critically Ill Patients

Clinical Trial Summary

To investigate natural killer (NK) cell activities, circulating cytokine levels and peripheral blood mononuclear cell (PBMC) cytokine production status in critically ill patients.

Clinical Trial Description

Blood samples were collected < 24 hours after admission from 24 intensive care unit (ICU) patients and 24 age-, sex-, and body mass index (BMI)-matched healthy controls. NK cell activities, cytokine concentrations and cytokine production by PBMCs and lipopolysaccharide (LPS)-stimulated PBMCs were measured. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02565589
Study type Observational
Source Yonsei University
Contact
Status Completed
Phase N/A
Start date April 2014
Completion date September 2015
View Details
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