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Relationship Between PTEN and Glycemic Variability and Outcome in Critically Ill Patients — GLUPTEN  

Critical Illness Clinical Trial

Official title:
Influence of PTEN on Glycemic Variability and Clinical Outcome in the Critically Ill Patient.

Clinical Trial Summary

Glycemic variability in critically ill patients is a recognized negative prognostic factor. The molecular mechanisms determining inter-patients variability in glucose metabolism during stress are not fully understood. The Phosphatase and Tensin homolog (PTEN) is known to influence glucose homeostasis by interfering in intracellular insulin signaling.

Aim of this study is to ascertain whether differential expression of PTEN in critically ill patients correlates with glycemic variability and clinical outcome.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01796847
Study type Observational
Source University of Roma La Sapienza
Contact
Status Completed
Phase N/A
Start date December 2012
Completion date May 2015
View Details
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