Critical Illness Clinical Trial
Official title:
Pharmacokinetics of Micafungin in Critically Ill Patients With Invasive Candidiasis
A study of micafungin in ICU versus non-ICU patients showed a significantly lower treatment
success in ICU patients compared with non-ICU patients. It is known that in critically ill
patients, alterations in function of various organs and body systems can influence the
pharmacokinetics and hence the plasma concentration of a drug. The pharmacokinetic
parameters of micafungin in critically ill patients are most likely different, but this has
not been specifically studied.
The pharmacokinetic parameters of micafungin in critically ill patients will be established
and plasma concentrations of micafungin will be correlated with disease severity.
n/a
Observational Model: Case-Only, Time Perspective: Prospective
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