Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Other |
Rate of Patients with Head of the Bed Elevated |
30 degrees in patients under mechanical ventilation |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Other |
Incidence of Early Reintubation |
Less than 48 hours after extubation |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Other |
Incidence of Accidental Extubation |
Rate of accidental extubation |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Other |
Rate of Central-Line Catheter Use |
Use of central-line catheter use |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Other |
Rate of Vesical Catheter Use |
Use of vesical catheter |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Other |
Rate of Adequate Prophylaxis for Venous Thromboembolism |
Adequate prophylaxis for venous thromboembolism |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Other |
Rate of Adequate Glycemic Control |
Adequate glycemic control |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Other |
ICU Readmission |
Readmission less than 24 hours after discharge |
From date of randomization until the date of hospital discharge or death, whichever comes first, assessed up to 90 days |
|
Other |
ICU Mortality |
ICU mortality rate |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Primary |
Intensive Care Unit Length of Stay |
Time until discharge from the intensive care unit |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Secondary |
In-Hospital Mortality |
Any death during hospital stay |
From date of randomization until the date of hospital discharge or death, whichever comes first, assessed up to 90 days |
|
Secondary |
Standardized Resource Use |
Calculated based on length of stay in the intensive care unit and adjusted for severity of acute illness |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Secondary |
Standardized Mortality Rate |
Ratio of observed deaths to expected deaths |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Secondary |
Incidence Density of Central Line-Associated Bloodstream Infection (CLABSI) |
Following the Centers for Disease Control/National Healthcare Safety Network (CDC/NHSN) Surveillance Definition of Healthcare-Associated Infection 2019 |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Secondary |
Incidence Density of Ventilator-Associated Pneumonia (VAP) |
Following the Centers for Disease Control/National Healthcare Safety Network (CDC/NHSN) Surveillance Definition of Healthcare-Associated Infection 2019 |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Secondary |
Incidence Density of Urinary Tract Infection Associated with Catheter |
Following the Centers for Disease Control/National Healthcare Safety Network (CDC/NHSN) Surveillance Definition of Healthcare-Associated Infection 2019 |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Secondary |
Ventilator-Free Days at Day 28 |
Survival time free of invasive mechanical ventilation from ICU admission to day 28. |
28 Days |
|
Secondary |
Patient-Days Receiving Oral or Enteral Feeding |
Use of enteral or oral feeding |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Secondary |
Patient-Days Under Light Sedation or Alert and Calm |
Defined as a Richmond Agitation-Sedation Scale (RASS) -3 to +1 |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|
Secondary |
Rate of Patients Under Normoxia |
Defined as oxygen saturation (SpO2) between 92% and 96% |
From date of randomization until the date of ICU discharge or death, whichever comes first, assessed up to 90 days |
|