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Cranial Nerve Diseases clinical trials

View clinical trials related to Cranial Nerve Diseases.

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NCT ID: NCT06417216 Recruiting - Clinical trials for Internuclear Ophthalmoplegia

Head-Cancelled Virtual Reality for Ocular Cranial Nerve Palsies

OCNP
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

This study is investigating whether eye exercises for abducens palsy and internuclear ophthalmoplegia increase ocular range of motion in the paretic direction when performed in virtual reality under head-cancelled compared to head-active conditions.

NCT ID: NCT04151082 Recruiting - Clinical trials for Head and Neck Carcinoma

High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer Survivors

Start date: October 31, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This phase I/II trial studies the side effect and best dose of steroid therapy (prednisone or methylprednisolone) in improving symptoms of late radiation-associated lower cranial neuropathy in oropharyngeal cancer survivors. Steroid therapy with prednisone or methylprednisolone may help to improve symptoms associated with late radiation-associated lower cranial neuropathy.

NCT ID: NCT03659760 Recruiting - Clinical trials for Cranial Nerve Diseases

: Association of Melatonin Levels and Light and Noise Isolation in ICU

Start date: September 3, 2018
Phase: N/A
Study type: Interventional

Melatonin is secreted from the epiphyseal gland with a circadian rhythm and is known to be anti-inflammatory. In this study, it is planned to investigate the effect of sleep disruptions on melatonin levels and inflammation parameters in intensive care patients underwent transcranial surgery

NCT ID: NCT03270059 Recruiting - Clinical trials for Metastatic Malignant Neoplasm in the Brain

Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System

Start date: October 6, 2017
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well gadolinium and ferumoxytol magnetic resonance imaging (MRI) work in diagnosing patients with abnormalities in the central nervous system. Diagnostic procedures, such as gadolinium and ferumoxytol MRI, may help find and diagnose abnormalities in the central nervous system.

NCT ID: NCT02978911 Recruiting - Cranial Nerve Palsy Clinical Trials

Cranial Nerves Tractography

CN Tracto
Start date: July 12, 2016
Phase: N/A
Study type: Interventional

Introduction: The skull base tumors surgery remains a challenge since numerous cranial nerves or vessels closely surround them. Recently, diffusion tensor imaging has developed with the tractography following white fibers and visualizing functional tracts. Cranial nerves tractography could allow predicting their displacement by skull base tumors that may help the surgeon to spare them along the surgery. Methods: Preoperative cerebral MRI was performed on patients who presented with skull base tumors. A 3 tesla MRI machine was used to acquire DTI sequence with specific parameters: 32 directions, slice thickness 2 mm, echo time 86 ms, repetition time 12000 ms, matrix 128x128, b-value 1000 s.mm-1. An anatomic sequence hyperT2 was overlaid as reference. Distortion was corrected by topup and eddy functions from FSL. Cranial nerves fibers were probabilistically tracked with Mrtrix3. Cranial nerves were selected according to their location around the tumor. The "radiological" expected position of the cranial nerve was compared to its "operative" real position.

NCT ID: NCT02149355 Recruiting - Clinical trials for Fourth Cranial Nerve Palsy

Teeth and Jaw Misalignment in Patients Suffering From Congenital Fourth Cranial Nerve Palsy

IVPareseZahn
Start date: March 2014
Phase: N/A
Study type: Observational

Patients suffering from congenital fourth cranial nerve palsy may have misalignment of jaws as well as teeth due to head tilt in childhood.