Effects of Exercise Training on Patients With Long COVID-19

Long COVID-19 Clinical Trial

Official title: Effects of Exercise Training on Patients With Long COVID-19, a Single-center, Randomized, Controlled Study

Status Completed

Clinical Trial Summary

Effects of Exercise training on Patients With Long COVID-19, is a single-center, randomized, controlled trial designed to evaluate the effects of 4- week aerobic exercise administered to patients with long COVID-19 symptoms. The main outcome is cardiopulmonary fitness and long COVID-19 symptom improvement. Quality of life, depression, anxiety, insomnia status and perceived stress will also be assessed before and after the exercise program.

Clinical Trial Description

Long COVID-19 symptoms are characterized by systemic deterioration of the entire body, leading to significant physiological and functional imbalances. Common symptoms may be related to decreased short-term or long-term exercise capacity resulting from organ tissue damage, such as myocardial and pulmonary dysfunction. Currently, even vaccines and medications cannot effectively address the long-term consequences of COVID-19. Exercise training has been proven to improve exercise capacity and quality of life during the recovery period for various chronic disease patients.

A total of 24 patients will be included in the study. Following informed consent and baseline testing, the participants will be randomized in a 1:1 fashion to receive a 4-week aerobic exercise training or attention control.The main objective is to assess the effects of a 4-week aerobic exercise training program on cardiopulmonary fitness and long COVID-19 symptom improvement. Secondary objectives include: to characterize baseline and intervention-related changes in quality of life, depression, anxiety, insomnia status and perceived stress status. ;

Related Conditions & MeSH terms

• COVID-19
• Long COVID-19

• NCT number: NCT05961462
• Study type: Interventional
• Source: Guangdong Provincial People's Hospital
• Status: Completed
• Phase: N/A
• Start date: January 10, 2023
• Completion date: August 30, 2023