Mortality, Gravity Predictive Factors and Clinical Evolution of Older COVID-19 Patients in Short Geriatric Services.

COVID-19 Clinical Trial

— GERICOVID  

Official title:

Analysis of Mortality, Gravity Predictive Factors and Evolution of Clinical Characteristics of Older Patients Hospitalized for COVID-19 in Short Geriatric Services.

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT05455892
• Other study ID #: AGORA n°36
• Status: Active, not recruiting
• Start date: July 23, 2020
• Est. completion date: September 30, 2022

Study information

• Verified date: July 2022
• Source: Hospices Civils de Lyon
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Since the beginning of the year 2020, clinical characteristics of a new disease as the global COVID-19 epidemic has spread in France. People over 70 years of age are the more concerned by this virus in proportion and in gravity with some atypical first symptoms compared to younger patients. Evolution of the disease is variable from forms with few symptoms to severe forms sometimes quickly lethal.

GERICOVID LYON is a descriptive analysis of all patients over 70 years of age hospitalised for COVID-19 in short geriatric unities of University Hospital of Lyon This study will allow more comprehension about COVID-19 in older people. The role of predictive factors, pre-existing comorbidities and the nature and frequency of complications in a short period will be investigate. Treatments practices will be analysed too.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 450
• Est. completion date: September 30, 2022
• Est. primary completion date: November 1, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 70 Years and older

Eligibility

Inclusion Criteria:

• Patient over 70 years of age.

• Patient hospitalized in short geriatric units in University Hospital of Lyon.

• Patient diagnosed with COVID-19 (positive Polymerase Chain Reaction or a high presumption of COVID-19 based on clinical and/or scannographic evidence).

• Patient Informed and non-opposed to the research (Patient informed of the study by his medical doctor during hospitalization or by post, thanks to a generic information sheet dedicated to COVID-19 researches).

Exclusion Criteria:

• Patient opposed to the research.

Related Conditions & MeSH terms

• COVID-19

Intervention

Other:
• Clinical data collection during hospitalization in short geriatric units.
Retrospective clinical data collection, at time of infection and 10 days later. Correlation between mortality and gravity. Identification of predictive mortality factors such as frailty, preexisting comorbidities, complications and treatments. Description of medical prescription evolutions.

Locations

Country	Name	City	State
France	Service de gériatrie aigue de l'hôpital de la Croix Rousse. Hospices Civils de Lyon	Caluire-et-Cuire	Rhone
France	Service de gériatrie aigue de l'hôpital Edouard Herriot, Pavillon T. Hospices Civils de Lyon	Lyon	Rhone
France	Service de gériatrie aigue de l'hôpital Edouard Herriot. Hospices Civils de Lyon	Lyon	Rhone
France	Service de gériatrie aigue de l'hôpital Lyon Sud. Hospices Civils de Lyon	Pierre-Bénite	Rhone
France	Service de gériatrie aigue de l'hôpital des Charpennes. Hospices Civils de Lyon	Villeurbanne	Rhone

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	In hospital mortality rate.	Observed mortality rate will be presented with its 95% confidence interval.	During patient hospitalization, an average of 10 days.