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NCT05238623 Clinical Trial

Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19

COVID-19 Pneumonia Clinical Trial

Official title:
Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19 Symptoms

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT05238623
Other study ID # KIM-IV-EIT03
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date March 1, 2022
Est. completion date March 31, 2025

Study information
Verified date March 2024
Source Jena University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Investigation of the correlation of CT-morphological changes of the lung compared to regional ventilation distribution on electrical impedance tomography in patients with post-acute-Covid-19 symptoms.

Description:

Prospective non-interventional, monocentric observational study on imbalances in regional lung ventilation compared to chest CT in post-acute-Covid-19. The aim is to verify the agreement between computerized tomography derived imaging variables and electrical impedance tomography in detecting lung ventilation imbalances. The primary study objective is to match CT morphological changes in regional ventilation in post-acute-COVID-19 patients and/or changes in lung function examination, with changes that can be visualized by electroimpedance tomography.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 50
Est. completion date March 31, 2025
Est. primary completion date December 30, 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - all patients undergoing a Chest CT due to suspected post-acute-Covid-19-syndrome - >18 years - informed consent. Exclusion Criteria: - trauma patients and patients with unstable spinal injuries or fractures - patients with an BMI over 50 - patients with uncontrolled body movements - Patients with a pacemaker

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• additional EIT Measurement
Patients who receive standard CT and pulmonary function testing also receive electroimpedance tomography measurement. The lunghealthy Patients in the control group only receive a EIT.

Locations
Country Name City State
Germany Klinik für Notfallmedizin Jena Thuringia

Sponsors (1)
Lead Sponsor Collaborator
Jena University Hospital

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Correlation between tomography and electroimpedance tomography The primary study objective is to match CT morphological changes in regional ventilation in post-COVID patients and/or changes in lung function examination with changes that can be visualized by electroimpedance tomography. until May 2022
Secondary Correlation between lung function testing and electroimpedance tomography until May 2022
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