Impact of Covid-19 in the Emergency Department

COVID-19 Clinical Trial

Official title:

Impact of Covid-19 in the Emergency Department in a Tertiary Care Hospital, Nuremberg-Germany

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05150821
• Other study ID #: IC_2021_KNN
• Status: Completed
• Start date: September 1, 2020
• Est. completion date: July 1, 2023

Study information

• Verified date: August 2023
• Source: Paracelsus Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To investigate the effects of lockdown in the Emergency Department in a tertiary health care hospital, Nuremberg, Germany.

Description:

To investigate the effect of the first lockdown caused by the pandemic of Covid-19 in a tertiary health care hospital. Klinikum Nuremberg is one of the largest tertiary health care hospitals in Germany with two locations in Nuremberg. In the north department, around 150 outcome patients visit the Emergency Department every day.

During the pandemic in 2020 the capacities of the hospitals were saved for the patients with Covid-19. A decrease of patients presented in the ED was noticed. Controlling system and patient management provided the number of cases and correlated with the same period of time one year ago, before the pandemic.

For the classification of severity of diseases, different clinical diseases with severity scores were analyzed. Following diseases and scores were evaluated:

Pancreatitis -- > ranson score; ACS (acute coronary syndrome) --> Grace-Score; Pulmonary Embolism -- > sPESI (simplified Pulmonary Embolism Severity Index); Diverticulitis --> CDD (Classification of Diverticular Disease); Pneumonia -> crb65 (Confusion- Respiratory rate- Blood pressure- age ≥ 65 years);

Recruitment information / eligibility

• Status: Completed
• Enrollment: 599
• Est. completion date: July 1, 2023
• Est. primary completion date: July 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

Only patients who presented in the ED.

Exclusion Criteria:

none

Related Conditions & MeSH terms

• COVID-19
• Emergencies

Locations

Country	Name	City	State
Germany	Institute of Radiology and Nuclear Medicine	Nuremberg	Bavaria

Sponsors (1)

Lead Sponsor	Collaborator
Dr. Panagiota Manava

Country where clinical trial is conducted

Germany, 

References & Publications (5)

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Morgan C, Ahluwalia AK, Aframian A, Li L, Sun SNM. The impact of the novel coronavirus on trauma and orthopaedics in the UK. Br J Hosp Med (Lond). 2020 Apr 2;81(4):1-6. doi: 10.12968/hmed.2020.0137. Epub 2020 Apr 10. — View Citation

Tam CF, Cheung KS, Lam S, Wong A, Yung A, Sze M, Fang J, Tse HF, Siu CW. Impact of coronavirus disease 2019 (COVID-19) outbreak on outcome of myocardial infarction in Hong Kong, China. Catheter Cardiovasc Interv. 2021 Feb 1;97(2):E194-E197. doi: 10.1002/ccd.28943. Epub 2020 May 5. — View Citation

Wang Y, Han W, Pan L, Wang C, Liu Y, Hu W, Zhou H, Zheng X. Impact of COVID-19 on blood centres in Zhejiang province China. Vox Sang. 2020 Aug;115(6):502-506. doi: 10.1111/vox.12931. Epub 2020 Apr 29. — View Citation

Wexner SD, Cortes-Guiral D, Gilshtein H, Kent I, Reymond MA. COVID-19: impact on colorectal surgery. Colorectal Dis. 2020 Jun;22(6):635-640. doi: 10.1111/codi.15112. Epub 2020 May 22. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	ranson score	clinical severity index of pancreatitis. Estimates mortality of patients with pancreatitis, based on initial and 48-hour lab values. Min. 0 - Max. 11 points.	through study completion, an average of 1 year
Primary	Grace-Score	clinical severity index of ACS. Estimates admission untill 6 month mortality for patients with acute coronary syndrome. 108 points: low risk. Over 141-372 points: high risk.	through study completion, an average of 1 year
Primary	sPESI	clinical severity index of pulmonary embolism. Predicts 30-day outcome of patients with pulmonary embolism. Min 0 points- max. 6 points	through study completion, an average of 1 year
Primary	crb65	The CRB-65-score is a clinical score that is used to estimate the severity of community-acquired pneumonias. The score corresponds to the statistical probability of patients dying because of pneumonia. Min 0 points - highest score 4 points.	through study completion, an average of 1 year
Primary	CDD	clinical severity index of diverticulitis. Min 0 - max. 4	through study completion, an average of 1 year