Long COVID-19 Clinical Trial
— COVID-19Official title:
Internet-based Multidisciplinary Rehabilitation for Longterm COVID-19 Syndrome
Internet-based multidisciplinary interventions will be offered to participants suffering from longterm COVID-19 syndrome. Data will be collected by internet platform at Karolinska Institutet (BASS) before, after rehabilitation and at follow-up after 6 months. Both self-scored questionnaires and physical tests performed at home will be collected to understand the symptomatology, functioning and activity level. Rehabilitation during 8 weeks period will be given in groups as face-to-group, pre-recorded film sessions and by individual approach, the participants will use ExorLive app for physical activity.
Status | Recruiting |
Enrollment | 200 |
Est. completion date | December 31, 2022 |
Est. primary completion date | December 31, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 67 Years |
Eligibility | Inclusion Criteria: - confirmed COVID-19 infection - post-infection symptoms lasting longer than 3-6 months - clinically stable persons regarding symtoms or other co-morbidities - ability to participate in internet-based rehabilitation in group in Swedish. Exclusion Criteria: - uncertainty regarding covid-19 infection or co-morbidities started or exacerbated during the same time - alcohol and drug abuse - untreated psychiatric and somatic co-morbidities - undergoing medical or psychotherapeutic treatment or rehabilitation which can interact with rehabilitation outcomes. |
Country | Name | City | State |
---|---|---|---|
Sweden | St Göran Hospital | Stockholm |
Lead Sponsor | Collaborator |
---|---|
Danderyd Hospital | St Göran Hospital, Stockholm |
Sweden,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in health-related quality of life measured by Short Form-36 | Important sub scales: vitality, general health, physical functioning, pain. Scale varies between 0 and 100 (highest) | Investigators expect changes at 6 months follow-up after rehabilitation | |
Primary | Changes in heart rate variability during physical tests | Heart rate variability measured by puls oximeter during 2 physical tests | Investigators expect normalisation at 6 months follow-up | |
Secondary | Overall changed scores in validated questionnaires for fatigue, breathing, pain and sleep disorders | Validated self-scored questionnaires such as Multidimentional Fatigue Inventory - for fatigue (values 0-20), Clinical COPD Questionnaire - for breathing (0-50), Chronic Visual Analogue Scale - for pain (0-100), Insomnia Severity Scale - for sleep (0-21) and other questionnaires. | Investigators expect changes already at 6 months follow-up | |
Secondary | Changed functioning and activity | Functioning and activity will be evaluated by self-scored questionnaires and a new questionnaire Functional compass for COVID-19 based on ICF (International Classification of Functioning and Disability) | Investigators expect normalisation at 6 months follow-up |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT06073002 -
Effects of a Home-Based Exercise Intervention in Subjects With Long COVID
|
N/A | |
Active, not recruiting |
NCT05965752 -
RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Long COVID Symptoms
|
N/A | |
Active, not recruiting |
NCT05965739 -
RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS Interventions on Long COVID Symptoms
|
N/A | |
Recruiting |
NCT05747534 -
AT1001 for the Treatment of Long COVID
|
Phase 2 | |
Recruiting |
NCT05817032 -
Effect of Telerehabilitation Practice in Long COVID-19 Patients
|
N/A | |
Enrolling by invitation |
NCT06305806 -
RECOVER-AUTONOMIC: Platform Protocol, Appendix B (Ivabradine)
|
Phase 2 | |
Enrolling by invitation |
NCT06305780 -
RECOVER-AUTONOMIC Platform Protocol
|
Phase 2 | |
Enrolling by invitation |
NCT06305793 -
RECOVER-AUTONOMIC: Platform Protocol, Appendix A (IVIG)
|
Phase 2 | |
Not yet recruiting |
NCT06404047 -
RECOVER-ENERGIZE Platform Protocol
|
N/A | |
Not yet recruiting |
NCT06404073 -
RECOVER-ENERGIZE Platform Protocol_Appendix B (Structured Pacing (PEM))
|
N/A | |
Not yet recruiting |
NCT06404060 -
RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)
|
N/A | |
Active, not recruiting |
NCT05813574 -
Long Term Impact of COVID-19
|
||
Enrolling by invitation |
NCT05965726 -
RECOVER-VITAL: Platform Protocol, Appendix to Measure the Effects of Paxlovid on Long COVID Symptoms
|
Phase 2 | |
Not yet recruiting |
NCT06404099 -
RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)
|
Phase 2 | |
Not yet recruiting |
NCT06404112 -
RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)
|
Phase 2 | |
Not yet recruiting |
NCT06404086 -
RECOVER-SLEEP: Platform Protocol
|
Phase 2 | |
Recruiting |
NCT05922865 -
The Effect of Smart Sensor Combined With APP for Individualized Precise Exercise Training in Long Covid-19
|
N/A | |
Completed |
NCT04604704 -
Pilot Study Into LDN and NAD+ for Treatment of Patients With Post-COVID-19 Syndrome
|
Phase 2 | |
Recruiting |
NCT05379556 -
LOng COvid COmorbidities: Andrological, Reproductive, Sexual Dysfunctions in Patients Recovered From COVID-19
|
||
Recruiting |
NCT05293366 -
LOng COvid COmorbidities: Endocrine,Metabolic,Neuropsychiatric,Muscle,Cardiovascular,Pulmonary,Dermatologic Dysfunctions
|