COVID-19 Clinical Trial
Official title:
Open Label, Randomized Phase II Study to Evaluate the Viral Load Reduction of a Single Administration of Plitidepsin in Adult Patients With COVID-19 at Discharge From Emergency
The main objective of this study is to evaluate the efficacy and safety of a single dose of plitidepsin in order to reduce the viral load and symptoms recovery after discharge from Emergency.
More than a year after the appearance of the new SARS-COV-2 coronavirus, the search continues for an effective treatment to reduce the symptoms and infectivity of a pandemic that has left behind more than 120 million cases and more than 2.5 million deaths. Plitidepsin is an approved multiple myeloma drug in Australia that in both preclinical and clinical studies has shown a clear antiviral effect against SARS.COV-2 and, in this study, we propose to evaluate the efficacy of a single dose of plitidepsin 7.5 mg administered in 90 minutes through decreasing viral load at day 6 and symptoms recovery at day 14 with after the patient is discharged from Emergency. ;
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