COVID 19 Clinical Trial
Official title:
A Prospective Observational Autopsy Study of Neuropathology in Adults Intensive Care Unit Patients With COVID 19
This is a single center observational autopsy study, conducted during the first wave of the coronavirus disease (COVID-19) pandemic in France. The main objective is to evaluate brain damages in patients who died from COVID-19 to inform the cause of death. Investigations include macroscopic and histology examinations, and virology analyses.
Setting: academic center designed as a referral center for patients with COVID-19 Design:
single center observational autopsy study Participants: intensive care unit (ICU) adults who
died from confirmed COVID-19 during the first wave of the pandemic in France.
Oversight: As per legal health authority requirement only patients with suspected or
confirmed severe acute respiratory syndrome (SARS)- related to coronavirus 2 infection were
admitted to the ICU. The department of pathology and forensic medicine is allowed by legal
authority to perform autopsy of non-survivors from COVID-19 to inform the cause of death as
per ministerial decree of July 12 2017 and March 28, 2020. In this context, of autopsy for
medical purpose and public interest there is no requirement for institutional review board
submission. However, consent from patients legal representative or closest relatives is
required for autopsy.
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