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Clinical Trial Summary

Hydroxychloroquine and azithromycin have been proposed as treatment of COVID-19 patients, but few reports have assessed this combination therapy in critically ill COVID-19 patients.

Many raised concerns regarding the potential cardiac toxicity of this association.

The purpose of this monocenter retrospective observational study is to evaluate the safety of a short term treatment with hydroxychloroquine and azithromycin in critically ill patients admitted in ICU for severe COVID-19 with respiratory failure.

The main objective is to assess the incidence of severe cardiac arrhythmia e.g torsade de pointes and cardiac arrest or sudden death, during the treatment period.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04452617
Study type Observational
Source Institut Mutualiste Montsouris
Contact
Status Completed
Phase
Start date March 19, 2020
Completion date July 1, 2020

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