COVID Clinical Trial
Official title:
Experimental Expanded Access Treatment With Convalescent Plasma for the Treatment of Patients With COVID-19
NCT number | NCT04445207 |
Other study ID # | H000020420 |
Secondary ID | |
Status | No longer available |
Phase | |
First received | |
Last updated |
Verified date | May 2023 |
Source | University of Massachusetts, Worcester |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Expanded Access |
The purpose of this program is to see if giving convalescent plasma to individuals who test positive for COVID-19 may reduce their symptoms and help minimize complications from the illness.
Status | No longer available |
Enrollment | 0 |
Est. completion date | |
Est. primary completion date | |
Accepts healthy volunteers | |
Gender | All |
Age group | 12 Years and older |
Eligibility | Inclusion Criteria: - At least 12 years of age - Covid-19 Convalescent Plasma (CCP) treatment is in line with the patient's current goals of care (i.e. recipient cannot be DNI status) - Laboratory confirmed diagnosis of infection with SARS-CoV-2 that is severe or life threatening OR the individual is judged by the treating provider to be at a high risk of progression to severe or life-threatening disease. - Severe COVID-19 is defined by one or more of the following: 1. Dyspnea 2. Respiratory frequency = 30/min 3. Blood oxygen saturation = 93% 4. Partial pressure of arterial oxygen to fraction of inspired oxygen ratio < 300 5. Lung infiltrates > 50% within 24-48 hours - Life-threatening COVID-19 is defined as one or more of the following: 1. Respiratory failure 2. Septic shock 3. Multiple organ dysfunction or failure Exclusion Criteria: - History of prior life-threatening reactions to transfusion of blood products - Not receiving other therapies that would preclude plasma transfusion |
Country | Name | City | State |
---|---|---|---|
United States | UMass Medical School | Worcester | Massachusetts |
Lead Sponsor | Collaborator |
---|---|
Jonathan Gerber |
United States,
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