Physical Activity Levels in COVID-19 Patients Admitted to Intensive Care

COVID-19 Clinical Trial

Official title:

Physical Activity Levels in COVID-19 Patients Admitted to Intensive Care Requiring Invasive Ventilation: An Observational Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04396197
• Other study ID #: PhysioCOVID-19
• Status: Completed
• Start date: March 1, 2020
• Est. completion date: May 8, 2020

Study information

• Verified date: May 2020
• Source: University Hospital Birmingham NHS Foundation Trust
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This is an observational study exploring the levels of mobility and rehabilitation in patients admitted to critical care with a confirmed diagnosis of COVID-19

Description:

An admission to an intensive care unit (ICU) often results in significant muscle weakness and physical deconditioning, which can take many months or even years for recovery. Early and progressive programmes of rehabilitation are recommended to limit any muscle loss and support recovery as early as possible. Patients admitted to intensive care with COVID-19 have been found to require prolonged periods of mechanical ventilation, high sedation and neuromuscular blocking use and as a result require prolonged stays in the ICU. As yet no data exists to examine the specific physical impact this may have, or whether it is safe and feasible to commence this earlier rehabilitation within the ICU for patients with a diagnosis of COVID-19. Our study set out to evaluate the levels of rehabilitation which were delivered in a large acute NHS trust.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 92
• Est. completion date: May 8, 2020
• Est. primary completion date: May 8, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• having a confirmed diagnosis of COVID-19

• being mechanically ventilated for at least 24 hours

• surviving to critical care discharge.

Exclusion Criteria:

• none

Related Conditions & MeSH terms

• Ards
• COVID-19
• Critical Illness
• ICU Acquired Weakness

Intervention

Other:
• Physiotherapy
Daily physiotherapy to include respiratory care and rehabilitation based on the individual therapists clinical reasoning

Locations

Country	Name	City	State
United Kingdom	UHB NHS Foundation Trust	Birmingham

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital Birmingham NHS Foundation Trust

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mobility level	Highest level of mobility achieved at the point of ICU discharge	At ICU discharge, an average of 3 weeks
Primary	Time taken to first mobilise	Time taken to first mobilise, defined as sitting on the edge of the bed or higher	during ICU admission, up to 3 weeks
Secondary	Discharge location	Discharged to home, home with rehab, or a community rehab facility	Hospital discharge, up to 2 months