Follow-up of Respiratory Sequelae of Hospitalized Patients With COVID-19 — SISCOVID  

Covid19 Clinical Trial

Official title: Follow-up of Respiratory Sequelae of Patients Hospitalized With SARS-CoV-2: a Prospective Multicenter Observational Study

Status Completed

Clinical Trial Summary

The objective of this multicenter observational study is to describe respiratory sequelae of COVID-19 patients hospitalized for severe pneumonia requiring oxygen supply.

Clinical Trial Description

Main objective To assess respiratory sequelae after SARS-CoV-2 infection in hospitalized patients with severe pneumonia requiring oxygen supply and followed up for 6 months after hospital discharge (see primary and secondary outcomes).

Secondary objectives

To describe pulmonary sequelae according to :

• the unit in which the patient was hospitalized,

• the maximum oxygen flow rate required during hospitalization,

• McCabe score,

• age,

• tobacco consumption,

• biological data (e.g. blood count, CRP, fibrinogen, LDH, albumin, D-dimer, ferritin),

• number of days from onset of symptoms to hospitalization,

• co-morbidities (e.g. diabetes, hypertension, coronary artery disease/heart failure, mild to moderate COPD/respiratory failure, overweight),

• concomitant treatments (e.g. non-steroidal anti-inflammatory drugs, corticosteroids, immunosuppressants, ACE inhibitors)

• specific drug treatments administered to treat COVID-19 infection,

• non-drug treatments (invasive ventilation, non-invasive ventilation, postural treatment) to manage respiratory disorders of COVID-19 infection.

To assess the impact of factors of social inequality on the severity of COVID-19 infection.

Conduct of research Patients who have been hospitalized for severe pneumonia due to CoV-2 SARS infection will be seen in consultation at approximately 3 and 6 months after hospital discharge, as per standard practice. ;

Related Conditions & MeSH terms

• COVID-19
• Covid19
• Dyspnea

• NCT number: NCT04505631
• Study type: Observational
• Source: Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
• Status: Completed
• Start date: June 10, 2020
• Completion date: January 15, 2021