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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT04404361 Terminated - COVID-19 Clinical Trials

PRE-VENT Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer

Start date: May 22, 2020
Phase: Phase 2
Study type: Interventional

This is a Phase 2 randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of pacritinib in hospitalized patients with severe COVID-19 with or without cancer.

NCT ID: NCT04404244 Completed - Clinical trials for Coronavirus COVID-19

Extraordinary Measures for Egyptian Children With Hemato-Oncological Disorders During COVID-19 Pandemic

PedCan-COVID
Start date: January 1, 2020
Phase:
Study type: Observational

This is a prospective follow-up non-intervention study that will be carried out at Hematology/ Oncology Department, Children's hospital, Ain-Shams University, Cairo, Egypt. All followed-up children below 18 years with cancer during the one year study period from May 2020 till Apr 2021 either at the out-patients clinic or inpatient department will be recruited.

NCT ID: NCT04404218 Active, not recruiting - COVID Clinical Trials

The Açaí Berry COVID-19 Anti-Inflammation Trial

ACAI
Start date: August 4, 2020
Phase: Phase 2
Study type: Interventional

The Açaí trial will be testing if the açaí berry extract, a safe natural product with anti-inflammatory properties, can be used as a treatment option in adult patients with COVID-19 in the community.

NCT ID: NCT04404179 Completed - COVID-19 Clinical Trials

Setting up a COVID-19 Care Facility at a Prison in Pakistan

Start date: March 27, 2020
Phase:
Study type: Observational

Presenting outline of the steps taken by our team to set up a Covid Care facility within the Prison setting. The facility was set up at Camp Jail (Lahore District Jail) located on Ferozpur Road, Lahore.

NCT ID: NCT04404062 Recruiting - COVID-19 Clinical Trials

Serological and PCR Testing for COVID-19

Start date: March 16, 2020
Phase:
Study type: Observational

Richmond Research Institute (RRI) is applying existing and new COVID-19 PCR and antibody tests to help develop methodologies which provide fast and accurate results. Infection with coronavirus (SARS-CoV-2) is currently a worldwide pandemic and reliable testing for COVID-19 is crucial to understand who is infected and therefore a risk to others by spreading the infection. RRI are currently carrying out the following tests: A. Using a membrane-based immunoassay to detect IgG and IgM antibodies to SARS-CoV-2 in whole blood, serum or plasma specimens helps to assess whether an individual has previously had the virus and is potentially immune B. Polymerase Chain Reaction (PCR) testing using an established method to check for active SARS-CoV-2 infections. C. Quantification of anti-SARS-CoV-2 IgG and IgM antibodies in whole blood samples. The above tests are being used by RRI to follow infections (PCR) and immunity (IgG) in their workforce, as well as their families (including children) and visitors to their site. Collecting this data allows the gathering of epidemiological data on SARS-CoV-2 including incidence, prevalence, information on asymptomatic carriers and efficacy of vaccination. Furthermore, identifying individuals that are infected with SARS-CoV-2 has great potential to improve health outcomes by allowing infected individuals to seek the correct medical treatment as well as self-isolate and reduce transmission.

NCT ID: NCT04403932 Completed - Clinical trials for Coronavirus Disease 2019 (COVID-19)

Increased Risk of Severe Coronavirus Disease 2019 in Patients With Vitamin D Deficiency

COVIT-D
Start date: April 17, 2020
Phase:
Study type: Observational

In this prospective observational study we aim to study the association of vitamin D deficiency with adverse clinical outcomes in patients infected with Coronavirus disease 2019

NCT ID: NCT04403906 Not yet recruiting - COVID Clinical Trials

Somerset and South Essex Coronavirus Antigen Testing

SOCRATES
Start date: June 2020
Phase: N/A
Study type: Interventional

This study is to evaluate the utility of the PCL Rapid Antigen Test for Coronavirus (COVID-19) in a real world clinical setting. The PCL test has completed laboratory validation and holds a European CE marking for in vitro diagnostic devices. These tests have been made available to South West Pathology Services as a donation in kind by iPP (Integrated Pathology Partnership). They have been widely used in South Korea. This study will test the practical delivery of the test in terms of time constraints and error rates. We will also compare the objective performance to the current standard diagnostic test for COVID-19 and against a proven serological antibody test when a suitable reference testing becomes available. We will recruit patients having a SARS CoV-2 PCR swab test and ask for consent to test them with the PCL antigen test in parallel. We aim to study 200 patients split across three sites; Musgrove Park Hospital, Basildon University Hospital and Southend University Hospital. The results will not be used to guide clinical decision making. Patients having a COVID PCR test will be asked to read the patient information sheet and asked if they would like to participate. The patients will be asked to have a second nasal/throat swab taken shortly after their swab for the PCR test. Written informed consent will be taken for whole blood or plasma left over from any routine clinical sample to be stored as anonymised samples for future testing once a reference test becomes available. We will report results of the onsite clinical diagnostic test and the PCL antigen test with the number of the kit used, and test date. Anonymised information about year of birth, gender and place of testing will be collected alongside date of onset, symptoms and immunodeficiency status or significant conditions.

NCT ID: NCT04403880 Completed - COVID-19 Clinical Trials

Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19

Start date: May 13, 2020
Phase:
Study type: Observational

The purpose of this study is to learn more about infection with and recovery from the virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Some people know this virus by the name "coronavirus." It can cause the disease called COVID-19. The information gained from the study will be used to help develop better tests for SARS-CoV-2 infection and COVID-19 disease and may help in developing future vaccines and treatments by allowing researchers to determine the difference between the body's immune response to natural SARS-CoV-2 infection and immunization with a SARS-CoV-2 vaccine.

NCT ID: NCT04403828 Completed - COVID 19 Clinical Trials

Impact of COVID-19 on Personal Protection Among Dentist in Egypt

Start date: May 20, 2020
Phase:
Study type: Observational

Dentist exposed to coronavirus (COVID-19) may not have adequate access to personal protective equipment (PPE), safety procedures, and diagnostic protocols. Our objective will be to evaluate the reality and perceptions about personal safety among dentist in Egypt

NCT ID: NCT04403685 Terminated - COVID Clinical Trials

Safety and Efficacy of Tocilizumab in Moderate to Severe COVID-19 With Inflammatory Markers

TOCIBRAS
Start date: May 8, 2020
Phase: Phase 3
Study type: Interventional

The trial evaluates the efficacy and safety of Tocilizumab, which rapidly reduces the inflammation process through inhibition of IL-6 in patients with moderate to severe COVID-19 with increased inflammatory markers. There will be two arms in the trial, one receiving the best supportive care, and the other receiving it plus tocilizumab. Patients will be followed until Day 29 after randomization.