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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT04870164 Terminated - COVID-19 Clinical Trials

Safety, Tolerability and PK of Ensovibep (MP0420 - a New Candidate With Potential for Treatment of COVID-19)

Start date: November 18, 2020
Phase: Phase 1
Study type: Interventional

This study will investigate how ensovibep is distributed throughout the body, the safety and the tolerability of ensovibep in healthy volunteers

NCT ID: NCT04869592 Active, not recruiting - COVID-19 Clinical Trials

A Clinical Trial to Evaluate the Recombinant SARS-CoV-2 Vaccine (CHO Cell) for COVID-19

Start date: April 25, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

phase I study will evaluate safety and immunogenicity of a recombinant SARS-CoV-2 vaccine (CHO cell) in Chinese healthy population aged 3 years and older. 300 subjects will be enrolled and divided into 5 age groups: 18-59 years old group, 60-69 years old group, ≥70 years old group, 9-17 years old group and 3-8 years old group. In each group, there are two regimen cohort: low-dose at 0,30, 60 schedule and high-dose at 0,30,60 schedule. The subjects in regimen cohort will be randomized to receive vaccines or placebos at a ratio of 2:1. Phase II clinical study will explore dose and immunization procedures in 5 age groups, including 18-59 years old group, 60-69 years old group, ≥70 years old group, 9-17 years old group, and 3-8 years old group, with a total of 3280 subjects.

NCT ID: NCT04869579 Not yet recruiting - Covid19 Clinical Trials

Selenium as a Potential Treatment for Moderately-ill, Severely-ill, and Critically-ill COVID-19 Patients.

SeCOVID
Start date: August 15, 2021
Phase: Phase 2
Study type: Interventional

Given its anti-viral, anti-oxidative, immune-enhancing, cytokine-modulating, and anticoagulant properties, the investigators hypothesize that Selenium infusion at supranutritional doses for moderately-ill, severely-ill, and critically-ill COVID-19 patients will prevent further clinical deterioration thus decreasing overall mortality and improving survival. To test this hypothesis, a prospective, single-center, phase II trial is proposed to assess the efficacy of Selenium in hospitalized adult patients with moderate, severe, and critical COVID-19 infections.

NCT ID: NCT04869397 Terminated - Covid19 Clinical Trials

Treatment of Respiratory Complications Associated With COVID-19 Using Umbilical Cord Mesenchymal Stromal Cells

ProTrans19+
Start date: June 14, 2021
Phase: Phase 2
Study type: Interventional

This is a randomized phase II placebo controlled clinical trial. Active arm: Allogeneic Wharton's jelly derived MSCs (WJ-MSCs). Both groups will receive standard of care treatment for COVID (e.g. dexamethasone)

NCT ID: NCT04869228 Terminated - COVID-19 Clinical Trials

A Phase 3 Randomized, Double-Blind Placebo Controlled, Multi-regional Trial to Evaluate the Efficacy and Safety of GT0918 for the Treatment of Mild to Moderate COVID-19 Male Patients

Start date: August 4, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of Proxalutamide (GT0918) in male outpatients with mild to moderate COVID-19 disease

NCT ID: NCT04869202 Completed - Perinatology Clinical Trials

Covid-19 Infection in Pregnancy

Start date: December 1, 2020
Phase:
Study type: Observational

Prospective study of both maternal and fetal outcomes of those pregnancies that were complicated by COVID-19 infection at various gestational ages. The follow up will be from the time the diagnosis was made till discharge of the mother and her baby from the hospital.

NCT ID: NCT04869072 Completed - COVID-19 Clinical Trials

Convalescent Plasma Therapy - Zurich Protocol

CPT-ZHP
Start date: April 29, 2020
Phase: Phase 1
Study type: Interventional

This is an open-label, single-center, phase I study to assess the safety and efficacy of convalescent plasma therapy (CPT) obtained from donors who were tested positive for SARS-CoV-2 and fully recovered from the infection and administered to patients who are infected with the new coronavirus and present dyspnea or a poor prognosis

NCT ID: NCT04868903 Active, not recruiting - Clinical trials for SARS-CoV-2 Infection

Low vs. Moderate to High Dose Vitamin D for Prevention of COVID-19

Start date: November 30, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the risks of COVID-19 in individuals from Chicagoland communities randomized to low (400 IU/day) vs. moderate (4,000 IU/day) or high (10,000 IU/day) dose vitamin D.

NCT ID: NCT04868890 Terminated - Covid19 Clinical Trials

A Study of Inhaled Ampion in Adults With Respiratory Distress Due to COVID-19

Start date: June 22, 2021
Phase: Phase 2
Study type: Interventional

This is phase II study to evaluate the safety and efficacy of inhaled Ampion in adults with respiratory distress due to COVID-19

NCT ID: NCT04868864 Recruiting - Clinical trials for Sars-CoV-2 Infection

The Ontario Multi-Regional Hospital COVID-19 Registry (COREG)- Recovery Trajectory Sub-study

COREG
Start date: May 15, 2021
Phase:
Study type: Observational [Patient Registry]

Radiological and lung function recovery following Covid-19 infection.