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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT05308680 Completed - COVID-19 Clinical Trials

Myocardial Injury After BNT162b2 mRNA COVID-19 Fourth Dose Vaccination Among Israeli Health Care Workers

Start date: January 6, 2022
Phase:
Study type: Observational

The aim of the study is to prospectively evaluate the incidence of myocardial injury after the administration of the fourth dose BNT162b2 mRNA vaccine (Pfizer-BioNTech) against COVID-19.

NCT ID: NCT05308615 Completed - COVID-19 Clinical Trials

Randomized Controlled Clinical Trial to Evaluate The Efficacy and Safety of Healthtone as Prophylaxis for COVID-19

Start date: March 3, 2021
Phase: N/A
Study type: Interventional

Background : Coronavirus disease known as COVID-19 is caused by the SARS-CoV-2. Transmission of SARS CoV-2 is spreading from human to human through direct or indirect droplets, this disease then spreads very quickly to various countries until it becomes a pandemic. Rhea® Health Tone is an essential oil made from Gardenia jasminoides, Commiphora myrrha, Boswellia serrata, Daucus carota, Foeniculum vulgarae, and Olea Europeae that have antimicrobial and anti-inflammatory effects. Rhea® Health Tone also has been registed on BPOM. Even so, the efficacy of Rhea® Health Tone still needs to be studied further. This research aimed to assess the efficacy and safety of healthtone as prophylaxis for COVID-19 in human resources at persahabatan central general hospital.The intervention group received Rhea® Health Tone 2 times supplementation 1 ml a day; meanwhile, the control group received placebo 2 times supplementation 1 ml a day.

NCT ID: NCT05308602 Withdrawn - COVID-19 Clinical Trials

A Study to Evaluate the Immunogenicity and Safety of SCTV01C and SCTV01E (Two Recombinant Protein COVID-19 Vaccines) in Population Aged ≥12 Years

Start date: April 1, 2022
Phase: Phase 2
Study type: Interventional

The objective of the study is to evaluate the immunogenicity and safety of SCTV01C or SCTV01E, comparing the immunogenicity data against Beta (B.1.351), Delta (B.1.617.2), Omicron (B.1.1.529) and other variants with Sinopharm inactivated COVID-19 vaccine or mRNA vaccine.

NCT ID: NCT05308576 Active, not recruiting - COVID-19 Clinical Trials

A Study to Evaluate the Efficacy and Safety of SCTV01E (a COVID-19 Vaccine) in Population Aged ≥18 Years

Start date: December 26, 2022
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the effectiveness of SCTV01E in participants aged ≥18 years.

NCT ID: NCT05308550 Completed - COVID-19 Clinical Trials

Clinical Evaluation of Rapid RNA Test for Covid-19

CERrnaTc-19
Start date: May 27, 2020
Phase: N/A
Study type: Interventional

A new Rapid RNA test for Covid-19 has been developed by Professor Cui and his team at the Department of Engineering Science at the University of Oxford. This can give results in 30 minutes which is much faster than the routine PCR test, which often takes 2-3 days to produce results. In this study we aim to establish the sensitivity of the rapid RNA test, which has never before been evaluated clinically. Preliminary anecdotal evidence suggests that the test is easy to use and appears to give valid results. This initial trial aims to establish whether the sensitivity of this tests is above the threshold of 90%. We aim to include at least 173 patients with symptoms of Covid-19 in Watford General Hospital.

NCT ID: NCT05308537 Completed - COVID-19 Clinical Trials

Randomized Controlled Trial of the Mindful Compassion Care Program in Reducing Psychological Distress Amongst Nurses During the COVID-19 Pandemic

MCCP-COVID19
Start date: January 27, 2023
Phase: N/A
Study type: Interventional

Recent studies have shown that nurses have been more affected by the COVID-19 pandemic than any other group of hospital workers in terms of anxiety, depression, and burnout. Several clinical studies had previously demonstrated the effectiveness of mindfulness and compassion interventions in reducing burnout and emotional distress amongst healthcare professionals. A parallel-group randomized controlled trial will assess the feasibility, acceptability, and efficacy of a mindfulness and compassion-focused programme on frontline nurses who had been working during the COVID-19 pandemic. Seventy-two participants will be divided equally into an intervention group and a control group. Primary outcome will be assessed using the Emotional Exhaustion subscale of the Maslach Burnout Inventory General Survey (MBI-GS). Secondary outcomes will be measured by the Cynicism and Professional Efficacy subscales of the MBI-GS; the Patient Health Questionnaire (PHQ-9); the Generalized Anxiety Disorder (GAD-7); the Insomnia Severity Index (ISI); the Impact of Stressful Events (IES-R); the Perceived Stress Scale (PSS); the Five Facet Mindfulness Questionnaire (FFMQ); and the Forms of Self-Criticising/attacking and Self-Reassuring Scale (FSCRS). The study aims to fill a gap in the literature and present a scientifically validated intervention for those healthcare professionals most exposed to the stressful conditions of working during the COVID-19 pandemic.

NCT ID: NCT05308524 Not yet recruiting - Clinical trials for ICU Scoring System in Covid 19

Scoring Systems covid19

Start date: April 1, 2022
Phase:
Study type: Observational

In this study, we planned to investigate the role and determine the predictive performance of both APACHE II and SAPS II scoring systems and compare them in COVID-19 patients admitted to the intensive care unit of Assiut University Hospital.

NCT ID: NCT05307601 Completed - COVID-19 Clinical Trials

Immune Response Following COVID-19 in Hemodialysis Patients

IMMUNOVIDIAL
Start date: September 1, 2020
Phase:
Study type: Observational

Patients with chronic kidney disease (CKD), particularly those undergoing hemodialysis (HD), are at high risk of a severe form of COVID-19. This study aims to characterize the inflammatory and antiviral response during SarsCov2 infection in adult

NCT ID: NCT05307588 Completed - Clinical trials for Psychological Distress

Psychological Distress During COVID-19 Pandemic

Start date: June 1, 2020
Phase:
Study type: Observational

Design, sample, and setting This is a cross-sectional study using an Internet-based self-administered questionnaire of closed-ended questions and using convenience sampling. In total, 612 undergraduate students completed the survey in Mansoura University. Data collection Data was collected anonymously through an online questionnaire created using the technology of Google Forms provided by Google ™ and was constructed in Arabic language. The questionnaire consisted of three sections. The first section assessed students' baseline characteristics including sex, age, area of study, academic level, residence, marital status, family members infected, close people infected, and knowing someone who died of the infection. The second section measured the psychosocial effects of COVID-19 pandemic using two instruments, University of California Los Angeles (UCLA) Loneliness Scale, version 324 and Depression Anxiety Stress Scale (DASS-21).19 The UCLA Loneliness Scale is a widely used self-report instrument of loneliness consisting of 20 items designed to measure both emotional as well as social loneliness. Response of each item was rated on a four-point scale from (1) never to (4) always felt as expressed in each item. Final score ranges from 20 to 80 with higher scores demonstrating higher feelings of loneliness. The scale's reliability was found to be high with alpha coefficients ranging from 0.89 to 0.94 for samples of students. The Arabic version of UCLA Loneliness Scale was used in the current study according to the Arabic translation in Egyptian culture by Daswqee.20 The correlation coefficients values were 0.76 for females and 0.74 for males.

NCT ID: NCT05307562 Active, not recruiting - Rehabilitation Clinical Trials

Efficacy of Respiratory Rehabilitation After COVID-19 Severe Infection

COVFIS2021
Start date: August 10, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effects of a training program in patients that have suffered a COVID infection