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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT05374772 Recruiting - COVID-19 Clinical Trials

A Retrospective Study in Patients With Mild to Moderate COVID-19

Start date: May 13, 2022
Phase:
Study type: Observational

The purpose of this retrospective study is to analyze real-world disease progression in mild-moderate COVID-19 patients with at least one risk factor for serve COVID-19 illness or death.

NCT ID: NCT05374668 Completed - Post-COVID-19 Clinical Trials

The Effects of Video-based Yoga Interventions for Patients With Post-corona Virus Disease

Yoga
Start date: March 22, 2021
Phase: N/A
Study type: Interventional

Aimed to understand if yoga exercises are superior to posture exercises as an alternative exercise therapy for relieving musculoskeletal pain, improving functional status, and improving quality of life during the post- corona virus disease (COVID-19) period?

NCT ID: NCT05374577 Recruiting - COVID-19 Clinical Trials

Pulmonary Vascular Dysfunction as a Cause of Persistent Exertional Dyspnea After Coronavirus Disease (COVID-19)

PulmVasC
Start date: April 15, 2022
Phase:
Study type: Observational

To identify pulmonary vascular disease in post/long-COVID-19 patients as a cause of dyspnea/exercise limitation and to differentiate it from other causes of dyspnea

NCT ID: NCT05373485 Active, not recruiting - COVID-19 Clinical Trials

Phase I Clinical Trial of COVID-19 mRNA Vaccine in Adults Aged 18 Years and Older

Start date: May 20, 2022
Phase: Phase 1
Study type: Interventional

To evaluate the safety and immunogenicity of the COVID-19 mRNA vaccine in people aged 18 years and older, 80 participants will be enrolled and divided into two groups: low- and high-dose groups. Each dose group will be divided into 2 age groups (20 people each):18 to 59 years old and ≥ 60 years old. Subjects will be randomized into vaccine group or placebo group in a ratio of 3:1. Subjects will receive 2 doses of either vaccine or placebo on Day 0 and Day 21, in which the low-dose group will received 0.3 ml of the study vaccine or placebo, and the high dose group will receive 0.5 ml of the study vaccine or placebo.

NCT ID: NCT05373472 Active, not recruiting - COVID-19 Clinical Trials

Phase II Clinical Trial of COVID-19 mRNA Vaccine in Adults Aged 18 Years and Older

Start date: July 6, 2022
Phase: Phase 2
Study type: Interventional

To evaluate the safety and immunogenicity of COVID-19 mRNA vaccine in people aged 18 years and older, 300 participants will be enrolled and divided into two groups: low- and high-dose groups. Each dose group (150 people) will be divided into 2 age groups (75 each):18 to 59 years old and ≥ 60 years old. The subjects will be randomized into vaccine group or placebo group in a ratio of 2:1. Subjects will complete 2 doses of vaccination on Day 0 and Day 21, in which the low-dose group will received 0.3 ml of the study vaccine or placebo, and the high dose group received 0.5 ml of the study vaccine or placebo.

NCT ID: NCT05373459 Completed - COVID-19 Vaccines Clinical Trials

Effect of a Third COVID-19 Booster Among Health Care Workers

Start date: May 16, 2022
Phase:
Study type: Observational

A new wave of COVID-19 infections, mainly caused by the Omicron/ Delta variant, has been sweeping the globe since the start of 2022. In response, the administration of a third dose of COVID-19 vaccine was considered to address potential waning immunity over time and reduced effectiveness against the Omicron/ Delta variant. The pandemic also resulted in many infections among health care workers (HCWs) and their households. In this study, a retrospective analysis would perform on risk of COVID-19 infection and their outcome in relation to their COVID-19 vaccination history by using the data repository from one of the Hong Kong private hospitals. HCWs were required to submit a standardized online self-declaration form for report of 1) demographic of the HCWs, 2) symptoms related history and 3) COVID-19 exposure history once they were COVID-19 confirmed by rapid antigen test against COVID-19 and/or polymerase chain reaction (PCR) test for COVID-19. Subsequent follow up such as contact tracing, COVID-19 PCR testing results of these HCWs and status of return to work were captured by the infection control team in a systematic manner.

NCT ID: NCT05373446 Not yet recruiting - COVID-19 Clinical Trials

Evaluation of SSD8432 and Ritonavir in Adult Subjects With COVID-19 Clinical Study

Start date: May 20, 2022
Phase: Phase 2
Study type: Interventional

This is a Randomized, double-blind, Placebo-Controlled, Phase II Clinical Study to evaluate SSD8432 in combination with Ritonavir in asymptomatic infections or mild/common safety study of efficacy and safety in adult subjects with COVID-19.

NCT ID: NCT05373433 Not yet recruiting - COVID-19 Clinical Trials

To Evaluate SSD8432/Ritonavir in Adults With COVID-19

Start date: May 26, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled, phase II/III clinical study to evaluate the efficacy and safety of SSD8432 in combination with ritonavir in adult subjects with mild/common COVID-19.

NCT ID: NCT05373420 Completed - COVID-19 Clinical Trials

COVID-19 Vaccination Uptake in Belgium : Sociodemographic and Socioeconomic Disparities

Start date: December 28, 2020
Phase:
Study type: Observational

In January 2021, the vaccination campaign against coronavirus disease 2019 (COVID-19) started in Belgium. The vaccination campaign was conducted in several phases, with the first phase targeting priority groups starting in January 2021. The second phase began in June 2021 with the invitation of everyone aged 18 years and older before extending access to 12 years and older from summer 2021. Children aged 5-11 were also invited for vaccination from December 2021 onwards. The presence of a social gradient in COVID-19 infections and subsequent outcomes has been clearly demonstrated. Individuals from lower socioeconomic groups, for example with lower income, lower education level or unemployed are more likely to be infected by the SARS-CoV-2 and to develop severe complications after the infection such as hospitalization, ICU admission or death. Certain sociodemographic characteristics such as male gender, older age, living in crowded households, or belonging to ethnic/racial minorities are also associated with a higher risk of COVID-19 infection and severe outcomes. In addition to disparities in infection, hospitalization and mortality, some studies have also documented a lower COVID-19 vaccination coverage among people from disadvantaged socioeconomic groups during COVID-19 pandemic. Despite widespread vaccine promotion efforts and the fact that Belgium has the 7th highest full vaccine coverage in the European Union (89% of people over 18 years old had completed their primary course of vaccination on 08 April 2022), concerns regarding vaccine equity remain. Vaccine uptake depends on a range of factors, including the socio-cultural environment, pre-existing health needs and individual choice. Identifying differences in vaccination between population groups is crucial to assess the effectiveness of the vaccination strategy in Belgium and its relationship to the further spread of COVID-19. The objective is to identify whether vaccination coverage has been equitable across Belgium and, if not, which groups of individuals are less likely to be covered by the COVID-19 vaccine, with respect to their sociodemographic (SD) and socioeconomic (SE) characteristics. This study therefore aims to highlight SD and SE disparities in the uptake of the first dose of COVID-19 vaccine in Belgium among people of 18 years and over.

NCT ID: NCT05373407 Completed - COVID-19 Clinical Trials

Low Versus Moderate-intensity Aerobic Training in Post-discharge COVID-19 Subjects

Start date: August 15, 2022
Phase: N/A
Study type: Interventional

The main purpose of this study is to compare the impact of low versus moderate-intensity aerobic training in post-COVID 19 older subjects. On exercise adherence and changes in physical fitness, psychological status, and quality of life after a 10-week intervention.