Covert Postoperative Stroke Clinical Trial
Official title:
Detection and Neurological Impact of CerebroVascular Events In Noncardiac Surgery PatIents: A COhort EvaluatioN
The NeuroVISION Study will characterize the incidence, impact, and risk factors of covert stroke in adults undergoing noncardiac surgery. We will determine the incidence of acute covert stroke using an MRI study of the brain in the days following noncardiac surgery. We will characterize the epidemiology and the impact of covert stroke in patients undergoing noncardiac surgery, and its association with cerebral deoxygenation.
At the University of Wisconsin a planned sub study of NeuroVISION is being conducted aiming
to enroll 100 patients with additional cognitive testing, MRI sequences and a preoperative
MRI scan.
At Hamilton Juravinski Hospital, Hamilton General Hospital, Auckland City Hospital and Prince
of Wales Hospital a planned sub study of NeuroVISION (PAFS - Perioperative Atrial
Fibrillation and Postoperative Stroke) is being conducted aiming to enroll 400 participants.
The purpose of this sub-study is to determine the prevalence of AF(Atrial Fibrillation)
before surgery (i.e. "background" AF), as well of the incidence of AF after surgery using the
Icentia CardioSTAT "patch-like" single lead heart rhythm monitor.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT05594966 -
Neuroimaging Combining Biomarkers for Identifying Long-term Cognitive Dysfunction and Delirium
|
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| Recruiting |
NCT04443933 -
Cerebral Small Vessel Disease and Perioperative Covert Stroke
|