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Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough

Cough Clinical Trial

Official title:
Office-Based Superior Laryngeal Nerve (SLN) Block for Treatment of Neurogenic Cough

Clinical Trial Summary

The purpose of this study is to evaluate if office-based injection of a local anesthetic/steroid combination at the area of one superior laryngeal nerve can decrease cough frequency and alleviate symptoms of chronic cough in patients with neurogenic cough.

Clinical Trial Description

Neurogenic cough is a chronic cough without a clear cause. It is thought to be related to irritation of a nerve that goes to the larynx (voice box). This can happen after a viral upper respiratory infection. Current treatment uses therapy or medications taken by mouth. Those medications can be sedating and not well tolerated. An alternative approach would be to perform an injection "nerve block", which is commonly done for other nerve disorders such as around the spine. This may help people with neurogenic cough also. We studied this recently in a small group of patients and found that patients had improvement in their cough symptoms (Simpson 2018). It would be helpful to study this in a larger group of patients using more methods of evaluating cough symptom severity. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04642352
Study type Observational
Source University of Alabama at Birmingham
Contact Blake Simpson, MD
Phone (205) 801-7863
Email blakesimpson@uabmc.edu
Status Recruiting
Phase
Start date January 3, 2022
Completion date October 2026
View Details
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